DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1774 and CG1635

DIOPT Version :9

Sequence 1:	NP_001287623.1	Gene:	CG1774 / 43722	FlyBaseID:	FBgn0039856	Length:	472	Species:	Drosophila melanogaster
Sequence 2:	NP_651873.3	Gene:	CG1635 / 43720	FlyBaseID:	FBgn0039854	Length:	448	Species:	Drosophila melanogaster

Alignment Length:	441	Identity:	207/441 - (46%)
Similarity:	296/441 - (67%)	Gaps:	14/441 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LARRSSWSTARRRRLLATSPPPLASQQMPRSYTLDNGPKVKSDH--------RSGTMVEVARVIR 69
            :..:..|...|.|..:     .|.::|:|.|:.|.........|        .||||.||.:.:.
  Fly     6 IGAQKCWGLIRTRNFM-----ELPTKQVPASFALFKRHYSPPTHIKQSAVANESGTMAEVKQGMM 65

  Fly    70 EQSGVDVGYHTIPKPRDHLLQHEPKREELPPRTMLDSHTTAILPLSSSELIRESYVNHLGRVRLG 134
            ::.|::.||:.:||.|:.||:::||.|:||||.|.||.|:||:|||:...:::.||.:||.||.|
  Fly    66 KRLGLEPGYNPLPKSREQLLKYQPKLEDLPPRAMQDSFTSAIIPLSTDRSLQDKYVTYLGNVRFG 130

  Fly   135 RIMEELDMFAVWICHRHVKLPKLPKGVPLPYTFVTLLVDKVEFTNLERLQVNQDIEISGHISWAG 199
            |::|::|:||.|.||:|:.||.||:||.|||||||:|||:::|||: .....|||.:|||:||.|
  Fly   131 RLLEDMDLFAAWCCHKHLVLPNLPEGVHLPYTFVTILVDRIDFTNV-LASGTQDIRLSGHVSWVG 194

  Fly   200 RSSMEITIYVRQLAHGEYIDVTKAIFVMVARNATNTGPAPINPIEVGDETEKLIWEQAEKRQKVR 264
            .||:|:.:::.|:..|.|..:|:|:|:|.||||.|||.||:||::..:|.||:|......|:|.|
  Fly   195 TSSIEVVVWLEQMVGGRYQKLTRALFLMAARNANNTGAAPVNPLQPANEEEKVILAGGADRKKKR 259

  Fly   265 KSSAMDSVFNSPPREHEQALMYEILKRTTPANSMDLNKRVLPPKCRWMEDSMQSTMIAPFPENRN 329
            :.....|:|...|.:.||.:|||:.|||||.|:::||||:|||.|||||||.|.:.|..|||:||
  Fly   260 QILCAQSIFKVEPNDPEQTIMYELYKRTTPTNTLELNKRILPPNCRWMEDSFQMSTIPSFPEHRN 324

  Fly   330 AQNTIFGGYLMRQAVEISFIMASIYLGDRPTLRCISDISFMHPVHVDRFLQLTAHVVYAAQNYVQ 394
            ..|.:|||:|||.|:|||:..|.:|...||.|..||||||..||.|:.|:::||:|||..:||||
  Fly   325 HHNRVFGGFLMRSALEISWAAAYLYCKTRPKLEHISDISFEKPVSVNSFIKMTAYVVYTKENYVQ 389

  Fly   395 LMTVAQIWDAKSGKVQTTNVFYLTYRADKVLDEVLPRSYREMLWYVHGRRK 445
            :||||.:.|.::|...|||.||.|:.:...:.|||||||.|.:||:.||||
  Fly   390 IMTVADVMDPQTGSQVTTNTFYYTFSSPDTVTEVLPRSYHETMWYIQGRRK 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1774	NP_001287623.1	BFIT_BACH	107..241	CDD:239526	69/133 (52%)
CG1774	NP_001287623.1	BFIT_BACH	310..421	CDD:239526	60/110 (55%)
CG1635	NP_651873.3	BFIT_BACH	103..228	CDD:239526	63/125 (50%)
CG1635	NP_651873.3	BFIT_BACH	305..418	CDD:239526	60/112 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456399
Domainoid	1	1.000	116	1.000	Domainoid score	I1965
eggNOG	1	0.900	-	-		E1_COG1607
Homologene	1	1.000	-	-		H8206
Inparanoid	1	1.050	134	1.000	Inparanoid score	I1842
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D261460at33208
OrthoFinder	1	1.000	-	-		FOG0002448
OrthoInspector	1	1.000	-	-		mtm6591
orthoMCL	1	0.900	-	-		OOG6_102325
Panther	1	1.100	-	-	P	PTHR12655
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1631
	12	11.800