DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1774 and T07D3.9

DIOPT Version :9

Sequence 1:	NP_001287623.1	Gene:	CG1774 / 43722	FlyBaseID:	FBgn0039856	Length:	472	Species:	Drosophila melanogaster
Sequence 2:	NP_493843.2	Gene:	T07D3.9 / 173471	WormBaseID:	WBGene00020311	Length:	441	Species:	Caenorhabditis elegans

Alignment Length:	468	Identity:	129/468 - (27%)
Similarity:	206/468 - (44%)	Gaps:	55/468 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LARSFGTALARRSSWSTARRRRLLATSPPPLASQQMPRSYTLDNGPKVKSDHR-SGTMVEVARVI 68
            :||.....::|.|      :.|.|.|..|........|.::.|  |....|.. |.|...||:.
Worm     2 IARHIANRISRFS------QTRSLRTIFPKTTVSIASRPFSTD--PDSLVDKMVSSTFCHVAKC- 57

  Fly    69 REQSGVDVGYHTIPKPRDHLLQHEPKREELPPRTMLDSHTTAILPLSSSELIRESYVNHLGRVRL 133
                          :| |...:.|...::|.|||:..|:...::|||:....::.|::....|||
Worm    58 --------------QP-DSFSEEEKNSKKLEPRTISHSYRKFVIPLSTDTNKQKQYLSAARSVRL 107

  Fly   134 GRIMEELDMFAVWICHRH-VKLPKLPKGVPLPYTFVTLLVDKVEFTNLERLQVNQDIEISGHISW 197
            |:|:|:||..||.:.:.| .....|.:.:.||.|.||..|.:::|.::| :..::|:.|.|.:::
Worm   108 GKILEDLDHMAVHVAYVHNSDNGTLDEPMTLPRTIVTASVKRIDFHDIE-MHPSRDVIIDGQVTY 171

  Fly   198 AGRSSMEITIYVRQLAH-GEYIDVTKAIFVMVARNATNTGPAPINPIEVGDETEKLIWEQAEKRQ 261
            ||.|||::.:.:.|... |....:.||.|:||:|:..:..    ..:.|...|.|.. ::||...
Worm   172 AGTSSMQVCLRLFQNDEIGNLNQLLKAEFIMVSRDPLDAS----KKVRVHGLTAKTP-DEAETIN 231

  Fly   262 KVRKS-SAMDSVFNSPPREHEQALMYEILKRTTPANSMDLNKRVLPPKCRWMEDSMQSTMIAPFP 325
            |.::. ..|.|..|..|...|..:::.:..... ..||..:..||.....||..:..|.....||
Worm   232 KTKEHFRRMGSSTNKQPTNEEFQVIHNMYSELV-GRSMVHDVAVLSNTEMWMHKTNLSVTEICFP 295

  Fly   326 ENRNAQNTIFGGYLMRQAVEISFIMASIYLGDRPTLRCISDISFMHPVHVDRFLQLTAHVVYAAQ 390
            |.:|....||||:|||:|:|::...|.:|...|..:|.:..|.|..||.:...|...:.|.|...
Worm   296 EYQNMYGKIFGGFLMRKALELAHTNAKLYCKGRVAIRSMDQIEFQKPVEIGHVLHFDSFVTYTDG 360

  Fly   391 NYVQLMTVAQIWD---------------AKSGKVQTTNVFYLTYRA---DKVLDEVLPRSYREML 437
            .|||:...|.|.|               .:..:| .||||..|..:   ..|| .|:|:.|....
Worm   361 KYVQVKVAATISDQHKLPELAKLNHPTLGEEARV-NTNVFNFTMESVENPNVL-RVVPKHYVHTT 423

  Fly   438 WYVHGRRKLLGAL 450
            .|:.|||.|...|
Worm   424 SYLEGRRLLNNTL 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1774	NP_001287623.1	BFIT_BACH	107..241	CDD:239526	40/135 (30%)
CG1774	NP_001287623.1	BFIT_BACH	310..421	CDD:239526	39/125 (31%)
T07D3.9	NP_493843.2	BFIT_BACH	87..207	CDD:239526	40/120 (33%)
T07D3.9	NP_493843.2	BFIT_BACH	280..416	CDD:239526	42/137 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162219
Domainoid	1	1.000	163	1.000	Domainoid score	I2401
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8206
Inparanoid	1	1.050	163	1.000	Inparanoid score	I2827
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55517
OrthoDB	1	1.010	-	-		D261460at33208
OrthoFinder	1	1.000	-	-		FOG0002448
OrthoInspector	1	1.000	-	-		mtm4781
orthoMCL	1	0.900	-	-		OOG6_102325
Panther	1	1.100	-	-	O	PTHR12655
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1631
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.910