DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1774 and ACOT7

DIOPT Version :9

Sequence 1:	NP_001287623.1	Gene:	CG1774 / 43722	FlyBaseID:	FBgn0039856	Length:	472	Species:	Drosophila melanogaster
Sequence 2:	NP_863654.1	Gene:	ACOT7 / 11332	HGNCID:	24157	Length:	380	Species:	Homo sapiens

Alignment Length:	174	Identity:	35/174 - (20%)
Similarity:	72/174 - (41%)	Gaps:	30/174 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 PENRNAQNTIFGGYLMRQAVEISFIMASIYLGDRPTLRCISDIS------FMHPVHVDRFLQLTA 383
            |::.|....:.||.:::...|...|:::.:...:...||::.::      |:.|:.:.....::|
Human    62 PDDANVAGNVHGGTILKMIEEAGAIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAHVSA 126

  Fly   384 HVVYAAQNYVQLMTVAQIWDAKSGKVQTTNVFYLTY------RADKVLDEVLPRSYREMLWYVHG 442
            .:.|.:::.|::.......:..:|..:.||...|.|      ..|||| ||.|..|........|
Human   127 EITYTSKHSVEVQVNVMSENILTGAKKLTNKATLWYVPLSLKNVDKVL-EVPPVVYSRQEQEEEG 190

  Fly   443 RRKL----LGALH------------LQPEYPDPIEVAKESSNHI 470
            |::.    |..:.            |.|| |:.:..::.|..|:
Human   191 RKRYEAQKLERMETKWRNGDIVQPVLNPE-PNTVSYSQSSLIHL 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1774	NP_001287623.1	BFIT_BACH	107..241	CDD:239526
CG1774	NP_001287623.1	BFIT_BACH	310..421	CDD:239526	18/107 (17%)
ACOT7	NP_863654.1	BFIT_BACH	48..163	CDD:239526	17/100 (17%)
		BFIT_BACH	222..345	CDD:239526	2/12 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	350..380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1607
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810