Protein Alignment rod and rod-1

DIOPT Version :9

• Sequence 1: NP_476705.1
• Gene: rod / 43719
• FlyBaseID: FBgn0003268
• Length: 2089
• Species: Drosophila melanogaster
• Sequence 2: NP_501200.1
• Gene: rod-1 / 177520
• WormBaseID: WBGene00018900
• Length: 2049
• Species: Caenorhabditis elegans
• Alignment Length: 2389
• Identity: 445/2389 - (18%)
• Similarity: 810/2389 - (33%)
• Gaps: 781/2389 - (32%)

  Fly   112 VNLEDVSLTGGTFRSIHQL---------------DQRFYF--TCKNGSIYSLSDIDE-------- 151
            |.|.||...|.....::::               ::||..  :|.:.:::||.:..:
 Worm    19 VGLYDVCTVGRILPLLNEMSIDKKSPAWKLKPKSNERFLVLASCSDLAVFSLGEKSDYSFNTGLG 83

  Fly   152 ---TCLETLGN---------------MSLNENETIACEKALLE-DVTIQRLSKGRSSCSVDCAVL 197
               |..|.||:               :||::.|....|.|..| |..:...:.  |.|.:   :.
 Worm    84 GAITDFEILGSSSFFVGVIEHRRIVILSLDKQEIYLNEPAPHEIDFVVCHTTS--SVCQL---IF 143

  Fly   198 LKR-------LLTGNISA--ENN----------QDDLEAQPGLVITGDQSTMNFRNAANDVTRI- 242
            ..|       .|.|:::|  |.|          |:......|..::   .:::....|.|:|.|
 Worm   144 GSRSDNWHTITLPGDVAASKETNRFENWHRDQIQEFFHQAMGKTVS---KSVDMSKVAGDITLIS 205

  Fly   243 NLPAQ-YGSLKQ---------------IFNLEHYIIALTDSG------------HLVE--ICPYT 277
            |.|.| :.|:.|               :..:|...:.:.|.|            |:.:  :..:.
 Worm   206 NGPLQTFASIDQQRGIHWCGLVESEFEVIGMEKQFLQVRDGGRFSLHLDTDGWIHVFDSLVSSFC 270

  Fly   278 RTVYMCQTTQQKNLLIEDLLVMECSEDNI----ELLVLTKSTAEGRFIKIVEYPTLNVKNEVEVP 338
            ....|..:...|   |.|.::::.:|..:    .:|||.:   :|...|::.|..||       .
 Worm   271 HEFDMKMSPDDK---ILDFVIIDKNEVEVPKMFAILVLPR---DGDSTKMMIYDRLN-------K 322

  Fly   339 DHAWLVRQPKCAVNLYY-------LAAKEVNQSSIP----SVVEMMLVSETDPSDRFKKLICKGR 392
            |:.:.:..........|       :|.:|:..|...    |.:.:..||::.|..||:.|:...|
 Worm   323 DNCFALDSSTSTTLFAYGGSDRVLIAVEELENSLADEQDGSQIVVRQVSQSRPEMRFESLLKNNR 387

  Fly   393 LEEAEEFGKQFELCLQPIYEAKAKRILVELCNSNSQNVDTKFQDLLQLLSQVESKAFIKS--HRM 455
            .||||:|...|.|.:|.:|:... ..|::.|:.:    |..|:.|:..:.|::....:..  ..:
 Worm   388 FEEAEKFAMAFMLDVQKVYKGHV-HYLMDSCDES----DESFETLMTKMGQIQDHNMVAETYFTL 447

  Fly   456 INLNSR-HILERYL-HEVKKRLTFEDDEEDMLEIDEQL-HRLKTLAIIDPYECN---------TD 508
            :.::.| ..:..|| |..|:|:|    :.|:|::.|.| :...|..||...|.|         |.
 Worm   448 VGMSRRCDRIRTYLTHAKKRRIT----DLDILKMIEALCYTWGTYRIIAGPEENEPSRPQVNETI 508

  Fly   509 WQKFI---YDNNLVRMVKSLFNTD--MPTACLIWRRHSSSILPLLNEDE----------LRTLLG 558
            |..|:   :|.|....:.:.|.:|  ...|.:|:.||..||...:.:||          .|..:.
 Worm   509 WDLFVEALHDANPWIEIYNEFISDAQFTQARVIFSRHGKSITDYMCDDEENTISRLETLFRMFID 573

  Fly   559 FIPSN-TKPFNVVQWL-RQFIPMVSNTHPSIMPFITDWSIEMTRNLQY--SPHWPDIGL------ 613
            .|.|: :|..||::.: ...:|........::|.:......:...|:|  |.:||:..:
 Worm   574 AISSDISKWSNVIEHVTTDILPACVMITEELIPCLESLITSLISLLEYRDSTNWPENAIKAASSY 638

  Fly   614 EFCTKILD------IFEEIQFTYSDVRRQQERN----VGKLRDLVNALQDLSVLKTNYNMGFTLD 668
            :..||||.      ..:.|...|.........|    :.:::.:...|.:|..||..|....:..
 Worm   639 DTMTKILSNNGNTPATQCILVMYGSKLGSSAGNKPSSMSRIKKIYYDLIELKRLKDVYECSISFS 703

  Fly   669 NYMQDSIDATALSILQHVQLD------KLQRLVKNFMYPIFQEKGRQPLDVIKQYISQLVASRLS 727
            .:...|.:.....|||:...:      |:::.||.||    .|:.......|..||..:..:.::
 Worm   704 VFQNMSSEQICHKILQNALANPNMTHAKIEKFVKPFM----AERHLDQEQTIVNYIQMMSGAAVT 764

  Fly   728 SSSWLDRAMACIEL---LHNEDSRLECALSVLQNAPVPWPDTLAPLIRLRASTHPLAVKINAEYE 789
            :::.......|::|   |.:|..|....:|:...|.:|||                     ||..
 Worm   765 NANLFGWEKQCVQLCASLMDETRRCCSIISIASTAKIPWP---------------------AELN 808

  Fly   790 IQVIKIMKVKYGWPADSSDINLELFMMRIV--KLNLPDML-------DDISALTKAAPELSTSAN 845
            ..|.||:       |..:.:..|:..|.:|  :..|..||       .||..||.....:.....
 Worm   809 EAVEKIL-------ASRTLLRSEIEQMHLVCKRTELYKMLSSYGFSRQDIELLTTPDSNMDIILT 866

  Fly   846 FNCCYQMARRGQVEMAYEFFKKLNGEKNSKSAKEVVEIMANILENSSSASFESDIKVQEHLNVLE 910
            ..|  .:|.|               ||.|:.. :|:::: ::|:....:|....::::
 Worm   867 IRC--MLAHR---------------EKASRFV-DVIKLV-DLLKAMQGSSQPRTLRIE------- 905

  Fly   911 LFKLFLPHVESVYERRYLVIKHRFRLRKFGILLSCSSELIPLHRRHCLLDEAIERIIERAQATLN 975
                   :|:|.                                       ||..::.....|::
 Worm   906 -------YVQSF---------------------------------------AIIHMMSHQDVTIS 924

  Fly   976 VSAFIASEISELCTALGLPKVFGLHRICQRIGCLPLSCALAYHVVSFVDCVPANAGEFVNLALEL 1040
            :..:|.|        ||       .|  :|:..:.|       |.||::|| |||....:..||.
 Worm   925 IINYIDS--------LG-------DR--ERVKTISL-------VFSFIECV-ANAPATGDNVLER 964

  Fly  1041 LVQQIESAKGKNQETAS--SLQLINENDPL-----SFYLAYE--------LLTSALLHESSRRHD 1090
                 |...|..:|..|  :.:..|.|||.     ...|..|        :|.|.|..|..:|..
 Worm   965 -----EKILGVGEELMSHYTCRDNNFNDPERRLKDELVLLREVQKTETKAVLLSELKDEDWQRRF 1024

  Fly  1091 LVELIKYIRVAVIHYPLDAIKSHYDGKEQAVNEHICRALDGISVALGETTINFSCALNGSFDVKT 1155
            |..||:    :.....|:..:..|.|...   ||:      |.:.|.:.|:        ..|:.|
 Worm  1025 LERLIE----SNSSMSLNLGRCSYMGISP---EHL------IEMILTKATV--------ENDMDT 1068

  Fly  1156 LTVPTTTKKRYSVSMFDEVE--VQPIQQ------------QPQKKSVGGRMAIVKFLARTLLLMV 1206
            :....|....:..|:.|...  ::||.|            .|.:..: .|...:.|:.:.:..:|
 Worm  1069 IVDSITNYVEFINSLTDSSREMLEPIVQILSWITFRLPKLLPNETEM-ARADYIAFVVKRIGRVV 1132

  Fly  1207 IETEPNNSLLMQVRNELPENTKADVESACADFFLSLEHLTKVKEHDAWYVMSQYLLDFQKQNCRT 1271
            .||....|.              ||.|...|:.|.||         |:|.:.::::   ||:.|.
 Worm  1133 RETLRRFSF--------------DVISDDLDYLLQLE---------AFYHLGEHII---KQSLRG 1171

  Fly  1272 KRIINEGFITLQLRRIFRNAMGSKDVNFIELFTMLVVDSEALALLEKLSV-EVKTDLQKINFLTL 1335
            :...||      .:.:||    |.|..|:.     ...|...:....|.: |.|..|...:|...
 Worm  1172 QENENE------KQEMFR----SDDDTFLP-----TDSSNPFSNQSSLRIFEFKRPLGTFDFSND 1221

  Fly  1336 SAMYHEHIEDLDSVHMIRTKRLKLFYYLEFCQQDHRIKGKFNADMDNIEDLLKEFHNKQLDV--Q 1398
            .|:: |.::.:.::.|:.....:. |..|....|   ..:|.:..:.:...|.......||:  :
 Worm  1222 PALF-EGVQGVLALAMVAPSVARP-YDSEISPDD---ANEFRSSWEQLNMFLAMHSQDLLDISAR 1281

  Fly  1399 LLERMSKDFGFDYQKILITQILSILSAQELRFEVKRDTFG--------------DEELVMLSSAQ 1449
            :.....|.:..:|.:.::.....|||..|...:.|:..|.              |..::.|...|
 Worm  1282 VFAGSLKCWAGEYLQGIVEMEQPILSVVERMLQQKKFDFWHAVTLLGGIPLERLDRAIIDLQKRQ 1346

  Fly  1450 EMRDMCQPYINEINNVELFTSKLKHFIEDINIYFYELYMCVINILMYFDSAPKEMEIWMNILHFL 1514
            .:|                 |..|..|:.:.:.|      |:::|      .:.||....|:...
 Worm  1347 GVR-----------------SSTKATIQYLQLAF------VMSLL------ARNMEKVPTIVSAY 1382

  Fly  1515 RHKMITRRRNRPGQVETDTWLKSQRENGVMPKISR------------YRLPFKPI---------V 1558
            ..|.:               :|...|.|:...|::            .|.|..|:         |
 Worm  1383 EQKYL---------------VKKLAEEGIRVSITQDFVDKVLQQAIDLRQPLSPLRLHDYVKKYV 1432

  Fly  1559 EQPLKDI-------------------------LDSELNVDNCQSWFPLIQMYTALKGSKDSSQNC 1598
            |:.:::.                         .|.|:..:..:.:....::...:...:|:|..|
 Worm  1433 EKLIRNSKISVGEYMVRYATLLIRKASVAGRHTDREIRKEEIEKYIEAARIALRIAEEEDASCIC 1497

  Fly  1599 DYF-CM---------SAVKNSISEYKSKNDSESWSLHPTNNAFLQSILRLVEKVNNPNKAFLILY 1653
            :|. |:         ..::..::.| .|..:|:..:....|  |:||:           |||..|
 Worm  1498 NYLHCLLYVVCPYNYEVIQFIVTSY-GKYATETVEIEFNKN--LKSIM-----------AFLWAY 1548

  Fly  1654 FVSNYARDGADQVEASYECWKFVKEKGHLITDPKSREQVAKVKRRYPIQKTQHLLYVYGLTDEKL 1718
            ..:|:       :......| |.|.:..|:.|.|.            .:||..:|..:|.:
 Worm  1549 QRTNH-------ISNEESIW-FTKRESVLMKDEKE------------FEKTGRMLDPFGHS---- 1589

  Fly  1719 LRQV-ENPTELIQALYHHELILKSSKV--DINALVAEIAKLHDLCLATIQYRLLQKWLALTMESA 1780
            ||.| |:....:...|:.:|.|.|..:  :.|:::     :.||.....||.....:|....|..
 Worm  1590 LRVVYEDDGSNMSDSYNSDLALSSDAMVYERNSVI-----ISDLPSLAEQYLPFHAFLLRKKEEI 1649

  Fly  1781 GD---GTILEE----------TFMEEQNWPEQANGAESSNSQ---------------------DA 1811
            .:   |.:..|          ||:.|.:|    ..:..|.||                     |.
 Worm  1650 DEIVMGIVKAELSIFNVPIWQTFLREVSW----LSSRFSRSQLLSSAIFAHANKYAKFGKSLPDG 1710

  Fly  1812 SENVNRAFYILSSWPKAEAVKFLVGLIFK------------GGSVNTS----------TQLQMYE 1854
            ..||  .:.:|:|..:...|...:.|:||            ...||.|          .|.:|.|
 Worm  1711 ERNV--IYELLNSASQRHVVVSTIALLFKRIILSDVKIELLQMGVNISERWTSDLTGEEQQEMEE 1773

  Fly  1855 CYSKLNDGSNSFTNTI--------SQRQFISIKCVHELKALGYKSNLEKFSDDH----------- 1900
            ..::|.||...|:..:        :::...:|:.|.||.:|.| :.:.::.|..
 Worm  1774 QSARLKDGIAKFSTELELKKNGLYNEKTADNIENVSELCSLIY-NEMVQWDDSRDVLKKCQVVDK 1837

  Fly  1901 ---CNKIDI------LKMIWQRNAQNPLSL-EVMANICLG--------------FDIHLPQIWNG 1941
               .|.:|:      |...|..:.|..:|: .|..|..:|              .|:.:| :::|
 Worm  1838 IAKANGLDLTALHEQLVFSWVEDTQTIISINHVDMNESIGGTSFLDHKDETDDQNDLRIP-LFDG 1901

  Fly  1942 ILKRMVMFHMVRELNALLDVLSCRPHLLHLDG-----------------------------LAQA 1977
            ||.::|:.....:...||..|.   .:|...|                             |:.|
 Worm  1902 ILDKVVVLCQRIDKKRLLTRLG---SILMRGGRKATGGYTAVVRATCIILRSFTDTEVSELLSGA 1963

  Fly  1978 WDYVLCHPLQNAVELRSFKQEEV----------LHKTLLRLQGCPVVHALNLLQFAQLCIVVHRP 2032
            ..:.||..|:|.:..|.|::.||          |.|:||:   ||                 .|.
 Worm  1964 DMFALCSTLENQLYERLFEKAEVKGDCKTDKMQLIKSLLQ---CP-----------------SRT 2008

  Fly  2033 HMAASLLSFCQSSEQRQKIKKMIHSHPVENLRQQILDLEDAGILPVVLN 2081
            |...:|:: |           :|..|..::.::.|....|.|.:||..|
 Worm  2009 HPMTALIA-C-----------LIIDHEFKDPKRDISLGWDVGCVPVSAN 2045

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rod	NP_476705.1	Rod_C	1544..2082	CDD:287465	133/735 (18%)
rod-1	NP_501200.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167579
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4256
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007375
OrthoInspector	1	1.000	-	-		oto20829
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15688
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3830
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.920