Protein Alignment pygo and Pygo2

DIOPT Version :9

• Sequence 1: NP_651872.1
• Gene: pygo / 43718
• FlyBaseID: FBgn0043900
• Length: 815
• Species: Drosophila melanogaster
• Sequence 2: NP_001280697.1
• Gene: Pygo2 / 68911
• MGIID: 1916161
• Length: 405
• Species: Mus musculus
• Alignment Length: 562
• Identity: 153/562 - (27%)
• Similarity: 188/562 - (33%)
• Gaps: 218/562 - (38%)

  Fly   289 PMNSLPMGSPMGNPIGSPLGPPSGPGPGNPG-------------NTGGPQQQ---QQQPPQPPMN 337
            |.:.|..||   .|...|..|.:|...|..|             ||.||...   :..||..||.
Mouse     8 PPDKLEGGS---GPAPPPAPPSTGRKQGKAGLQMKSPEKKRRKSNTQGPAYSHLTEFAPPPTPMV 69

  Fly   338 NGQMGPPPLHSPLGNGPTGHGSHMP--GGPIPGPGPGPGGLVGPGGISPAHGNNPGGSGNNMLGG 400
            :..:...|.....| .|...|:..|  |.|:|.     ||....||::   |..|.|.|.
Mouse    70 DHLVASNPFEDDFG-APKVGGAGPPFLGSPVPF-----GGFRVQGGMA---GQVPPGYGT----- 120

  Fly   401 NPGGGNSNNNGSNTSNASNNNQNPHLSPAAGRLGVPTSMQSNGPSVSSVASSSVPSPATPTLTPT 465
              |||                            |.|..::...|
Mouse   121 --GGG----------------------------GGPQPLRRQPP--------------------- 134

  Fly   466 STATSMSTSVPTSSPAPPAMSPHHSLNSAGPSPGMPNSGPSPLQSPAG----PNGPNNNNSNNNN 526
                          |.||        |..||:..||..||.  ..|.|    |:.|.|.:...|.
Mouse   135 --------------PFPP--------NPMGPAFNMPPQGPG--YPPPGNMNFPSQPFNQSLGQNF 175

  Fly   527 GPMMGQMIPNAVPMQHQQHMGGGPPGHGPGPM--PGMGMNQMLPPQQPSHLGPPHPNMMNHPHHP 589
            .|..||::|             ||.| |.|||  |.||.    ||:  ..||||
Mouse   176 SPPGGQVMP-------------GPVG-GFGPMISPTMGQ----PPR--GELGPP----------- 209

  Fly   590 HHHPGGPPPHMMGGPGMHGGPAGMPPHMGGGPNPHMMGGPHGNAGPHMGHGHMGGVPGPG-PGPG 653
                  |.|.....||...||:...|..|....|       .|..|..|       |.|| ||||
Mouse   210 ------PLPQRFTQPGAPFGPSLQRPGQGLPSLP-------PNTSPFPG-------PDPGFPGPG 254

  Fly   654 GMNG-----PPHP---HMSPHHGHPHH--HHNPMGGPGPNMFGGGGGGP----MGPGGPMGNMGP 704
            |.:|     ||.|   ...||.|.|..  :.|....| |:..|.|||.|    :.|.|..|.
Mouse   255 GEDGGKPLNPPAPTAFPQEPHSGSPAAAVNGNQPSFP-PSSSGRGGGTPDANSLAPPGKAGG--- 315

  Fly   705 MGGGPMGGPMGVGPKPMTMGGGKMYPPGQPMVFNPQNPNAPPIYPCGMCHKEVNDNDEAVFCESG 769
                      |.||:|         |||.             :||||.|..||||:.:|:.||:.
Mouse   316 ----------GSGPQP---------PPGL-------------VYPCGACRSEVNDDQDAILCEAS 348

  Fly   770 CNFFFHRTCVGLTEAAFQMLNKEVFAEWCCDKCVSSKHIPMV 811
            |..:|||.|.|:||:|:.:|..|..|.|.||.|:.:|.|..|
Mouse   349 CQKWFHRECTGMTESAYGLLTTEASAVWACDLCLKTKEIQSV 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pygo	NP_651872.1	PHD_dPYGO	749..802	CDD:277107	26/52 (50%)
Pygo2	NP_001280697.1	PHD_PYGO2	328..381	CDD:277106	26/52 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837986
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28KAX
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004253
OrthoInspector	1	1.000	-	-		otm43414
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23194
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4735
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.960