Protein Alignment gammaCOP and copb-1

DIOPT Version :9

• Sequence 1: NP_001263145.1
• Gene: gammaCOP / 43717
• FlyBaseID: FBgn0028968
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_494441.1
• Gene: copb-1 / 173656
• WormBaseID: WBGene00021292
• Length: 971
• Species: Caenorhabditis elegans
• Alignment Length: 1056
• Identity: 203/1056 - (19%)
• Similarity: 354/1056 - (33%)
• Gaps: 331/1056 - (31%)

  Fly    15 PSNAYQNLEKTSVLQETRTFNETPVNPRKCIHILTKILYLINQGEQLVAREATDCFFAMTKLFQS 79
            ||:|    |..|..|....|.:.  ..::.|..|.|::|:|..||:   ...:...:.:.....|
 Worm    15 PSDA----ELPSEAQLKEKFEKG--GDKERIEALKKLIYMILNGEK---TSQSMLMYVIRFCLPS 70

  Fly    80 KDVVLRRMVYL---GIKELSS---IAEDVIIVTSSLTKDMTGKEDLYRAAAIRALCSITDNTMLQ 138
            .:..|::::.:   .:.:..|   :..::|:|..:..||:....:..|.:.:|.||.:.:..:|:
 Worm    71 NEHTLKKVLLIFWECVPKTDSNGKLLHEMILVCDAYRKDLQHPNEFVRGSTLRFLCKLREPELLE 135

  Fly   139 AVERYMKQCI------VDKNAAVSCAALVSSLR-LANTAGDVVKRWANEAQEALNSDNIMVQYHA 196
            .:...::.|:      |.:||..:...:..:.. |...|.::|..:..:.|:|....|      |
 Worm   136 PLMPAIRACLEHRHSYVRRNAVCAIFTIYKNFEFLIPDAPELVTEYLEQEQDASCKRN------A 194

  Fly   197 LGLLYHI---RKSDRLA-----VSKLVNKLTRGSLKSPYAVCMLIRIACKLIEEEDIPSEELSDS 253
            ..:|.|:   |..|.|:     |....:.|....::..|.||            .:.|:|.   |
 Worm   195 FMMLLHVDQARALDYLSGCIDQVGSFGDILQLVIVELIYKVC------------HNNPNEA---S 244

  Fly   254 PLFTFIESCLRHKSEMVIYEAAHAIVNLKNTNPRMLSPAFSILQLFCSSPKATLRFAAVRTLNKV 318
            .....:.:.|:..|..|.||||..:|.|.|....:.:.|.:.:.|........::...:..|  |
 Worm   245 RFIRCVYNLLQSSSPAVRYEAAGTLVTLSNVPAAVKAAASAYIDLIVKESDNNVKLIVLDRL--V 307

  Fly   319 AMTHPAAVTTCNLDLEGLITDSNRSVA-----------TLAITTLLKTGAESSVERLMKQISTFV 372
            |:...::....   |:||:.|..|.::           :||:..:.....|..|..|.|:|:...
 Worm   308 ALRGSSSNEKI---LQGLVMDILRVLSSPGLEVRKKTLSLALDLVSSRNVEDMVMFLKKEINKTA 369

  Fly   373 AEISDE---FKVVVVQAICALCTKYPRKHTVLMNFLSGMLREEGGLEYKTSIVDTIITIIEE-NA 433
            .|.:||   ::..:|:.:.|...|:|                        .:..||:.::.| .:
 Worm   370 TESNDENGKYRQELVKTLHAATIKFP------------------------DVASTIVPVLMEFLS 410

  Fly   434 DAKESGLSHLCEFIEDCEH--VSLAVRILHLLGKEGPFAATPSKYIRFIYNRVIL---------- 486
            |..|...|::.:|:.:..|  .:|...||..|.:..||..:|:.::..::   ||
 Worm   411 DTNEKASSYVLQFVREAVHKLPNLKNAILGALREGIPFIQSPTIFMSALW---ILATYCEADGAL 472

  Fly   487 ----------------------------------------------------------------- 486
                                                                             
 Worm   473 DVLKLVKNSLGELPLVDSELSGQEEQKPEEQQPEQQQKQKPKVTADGTYATQTALSSTVTTSKKN 537

  Fly   487 ESPIVR--------------AAAVTAMAQ---------------FGASCPALLSNILVLL--GRC 520
            |.|.:|              |..:|.:||               |.|.|..:||:|:.|.  |.|
 Worm   538 EKPPLRRFLLDGEFFLGASLATVLTKLAQQFTELNGAASERANRFRAECMLILSSIIHLAKSGLC 602

  Fly   521 ----QMDPDDEVRDRATYYLSILNSERPELYKNYIIERENCSLALLEKSLVEHLNGDVDTRFDIS 581
                |::.||..|..||  :.||....|.|.:.|   .::|     :|||...|.....:|.|::
 Worm   603 IVHQQVNEDDLDRMGAT--IKILAQGIPGLDEQY---GDDC-----KKSLELMLGAKSISRLDVT 657

  Fly   582 IVPKAAIVKP-VIANDVMLVTSSAPRPPKITREEESAARLAQLPGIQVLGPIHRSTAP------- 638
            ....|:.... ..:.|.:.:..:........|..:....|..|...|.||     |||
 Worm   658 TEKMASTTAAGYRSKDFVEIDKTINFTQLSARSNQQGENLFDLSLSQALG-----TAPKAQKFDF 717

  Fly   639 --------IQLTESETEYTVQCIKHIFGQHVVFQFDCLNTLSDQILENVRVELTLPEGFTTRAVI 695
                    |||.........:...::....:|.....:|..|| .|:||.:||         |.:
 Worm   718 SSSKLGKVIQLAGFSDPIYAEAYVNVNQYDIVLDVLIVNQTSD-TLQNVSLEL---------ATV 772

  Fly   696 PCPKLPYNDLQTTFVIVEFPPDAANSIATFGATLRFVVKDCDPNTGEPESEEGYD--------DE 752
            ...||.......|..    |.|.:|..||        ||......|...|...||        :.
 Worm   773 GDLKLVDKPTPVTLA----PNDFSNIKAT--------VKVASTENGVIFSTISYDVTGSTSDRNC 825

  Fly   753 YMLEDLELTVADQI--QKTRKNNFQVSWDAADSEEWLQAEDTFVLSAVTTLQDAVN-----TIVK 810
            ..|:|:::.:.|.|  .......|:..|   ...||  .....|::.:..|:|.:|     |.:|
 Worm   826 VYLQDIKIDIMDYIVPGNVTDTEFRTMW---SDFEW--ENKVNVMTPIRDLRDFLNHLSTSTNMK 885

  Fly   811 IL----------GLGAANLSENVPEGTHLHTLLCSGTFRGG---------------------AEI 844
            :|          |..|||              ||:.:..|.                     ..|
 Worm   886 VLTGDAAIEGDCGFLAAN--------------LCAHSIFGEDALANVSVEKALPMDDSSPIVGHI 936

  Fly   845 LVRAKLALSEGVTLNL 860
            .:|||   |:|:.|.|
 Worm   937 RIRAK---SQGMCLTL 949

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaCOP	NP_001263145.1	SEC21	11..877	CDD:227565	203/1056 (19%)
		HEAT repeat	402..427	CDD:293787	2/24 (8%)
		HEAT repeat	439..465	CDD:293787	7/27 (26%)
		HEAT repeat	475..505	CDD:293787	10/133 (8%)
		HEAT repeat	512..538	CDD:293787	10/31 (32%)
		COP-gamma_platf	620..761	CDD:285908	37/163 (23%)
		Coatomer_g_Cpla	763..877	CDD:292991	28/136 (21%)
copb-1	NP_494441.1	COG5096	31..935	CDD:227427	188/1017 (18%)
		HEAT repeat	138..162	CDD:293787	4/23 (17%)
		HEAT repeat	174..222	CDD:293787	12/53 (23%)
		HEAT repeat	245..275	CDD:293787	9/29 (31%)
		HEAT repeat	284..308	CDD:293787	2/25 (8%)
		HEAT repeat	319..343	CDD:293787	5/23 (22%)
		Coatamer_beta_C	677..816	CDD:285019	35/165 (21%)
		Coatomer_b_Cpla	825..953	CDD:291472	30/147 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910