Protein Alignment gammaCOP and AgaP_AGAP003359

DIOPT Version :9

• Sequence 1: NP_001263145.1
• Gene: gammaCOP / 43717
• FlyBaseID: FBgn0028968
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: XP_314261.5
• Gene: AgaP_AGAP003359 / 1275037
• VectorBaseID: AGAP003359
• Length: 574
• Species: Anopheles gambiae
• Alignment Length: 648
• Identity: 129/648 - (19%)
• Similarity: 219/648 - (33%)
• Gaps: 178/648 - (27%)

  Fly   264 RHKSEMVIYEAAHAIVNLKNTNP-RMLSPAFSILQLFCSSPKATLRFAAVRTLNKVAMTHPAAVT 327
            ::....::||....|:|:::.|. |:|  |.:||..|..:....:||..:.||.|.......||.
Mosquito    16 KNAGNAILYETVLTIMNVESENSLRVL--AVNILGRFLLNNDKNIRFIGLLTLVKTVHKDMTAVQ 78

  Fly   328 TCNLDLEGLITDSNRSVATLAIT---TLLKTGAESSVERLMKQISTFVAEISDEFKVVVVQAICA 389
            ...:.:...::|.:.|:...|:.   ||:.|   .::|.:::::..::.....|.|.:....|..
Mosquito    79 RHRITILECLSDGDPSIQRCAMELSFTLINT---QNIEMVVRELLRYLESTDAEMKALCSSKIVL 140

  Fly   390 LCTKYP---RKH-TVLMNFLSGMLREEGGLEYKTSIVDTIITIIEENADAKESGLSHLCEFIEDC 450
            ....|.   |.| .||:..|:     ..|...:..::.:.|.:|..:.       .|...||.|
Mosquito   141 AAETYSPSIRWHLDVLLRILT-----IAGNNIRDDVISSTIQLISNSP-------QHEQRFITD- 192

  Fly   451 EHVSLAVRILHLLGKEGPFAATPSKYIRFIYNRVILES--PIVRAAAVTAMAQFGASCPALLSNI 513
                                    |....|.|...||:  |:|: .||..:.::|.|
Mosquito   193 ------------------------KMWEAIMNMNQLENRQPLVQ-VAVWTIGEYGES-------- 224

  Fly   514 LVLLGRCQMDPDDEVRDRATYYLSILNSERPEL---YKNYIIERENCSLALLEKSL------VEH 569
                     ...||. :...:|..:|.:  |:|   .|.||:    .|||.:...:      :::
Mosquito   225 ---------GGFDEF-ELIEHYRQLLWA--PQLSITTKQYIL----VSLAKISVRIDGCTPEIQN 273

  Fly   570 LNGDVDTRFDISIVPKAAIVKPVIANDVMLVTSSAPRPPKITREE----ESAARLAQLPGIQVLG 630
            :........:|.:..:|.....:..|...|.||...:.||:...|    |..|..|.....:|
Mosquito   274 IINAFRVHMNIDLQQRANEFSQLFTNYKHLRTSLLEKMPKLKLSELTTSEYNADFASGESSEV-- 336

  Fly   631 PIHRSTAPIQLTESETEYTVQCIKHIFGQHVVFQFDCLNTLSDQILENVRVELTLPEGFTTRAVI 695
            ...:...|:...|...:   ..:..:.|       ||.:  ||            ..|....||:
Mosquito   337 EQQQQEEPVPAPEPSNQ---DILLDLLG-------DCFS--SD------------GNGNNALAVV 377

  Fly   696 PC--PKLPYNDLQTTFVIVEFPPDAANSIATFGATLRFVVKDCDPNTGEPESEEGYDDEYMLEDL 758
            |.  |..|.:.|||:|        ....::|..          :.|...|.: .|.|.  .|:.|
Mosquito   378 PVTQPAAPQSYLQTSF--------NQTGLSTMN----------NYNNNGPMA-PGTDS--FLDLL 421

  Fly   759 ELTVADQIQKTRKNNFQVSWDAADSEEWLQAEDTFVLSAV----TTLQD---------------- 803
            .|..|:|.|.:::.....:.....:.|....:|..:...|    ||:.|
Mosquito   422 GLAAANQTQPSQQQTINYTPATIPAIEVYHKDDIHIRFLVHPQQTTVHDREAPSTTPARITVQTT 486

  Fly   804 --AVNTIVKILGLGAA------NLSE-----NVPEGTHLHTLLC------SGTFRGGAEILVR 847
              :..||.|.|...|.      .|.|     ..|.||.:..||.      ||...||..:.||
Mosquito   487 NGSQATIEKFLFQAAVPKAFVLTLREPSGTVMPPGGTIMQDLLIARQTGQSGGAAGGLRMKVR 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaCOP	NP_001263145.1	SEC21	11..877	CDD:227565	129/648 (20%)
		HEAT repeat	402..427	CDD:293787	2/24 (8%)
		HEAT repeat	439..465	CDD:293787	4/25 (16%)
		HEAT repeat	475..505	CDD:293787	10/31 (32%)
		HEAT repeat	512..538	CDD:293787	3/25 (12%)
		COP-gamma_platf	620..761	CDD:285908	26/142 (18%)
		Coatomer_g_Cpla	763..877	CDD:292991	27/124 (22%)
AgaP_AGAP003359	XP_314261.5	Adaptin_N	<1..301	CDD:279882	67/351 (19%)
		Alpha_adaptinC2	449..569	CDD:197886	23/101 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910