Protein Alignment nyo and cutl-18

DIOPT Version :10

• Sequence 1: NP_651871.2
• Gene: nyo / 43716
• FlyBaseID: FBgn0039852
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: NP_505875.2
• Gene: cutl-18 / 179565
• WormBaseID: WBGene00009830
• Length: 801
• Species: Caenorhabditis elegans
• Alignment Length: 756
• Identity: 140/756 - (18%)
• Similarity: 233/756 - (30%)
• Gaps: 290/756 - (38%)

  Fly   139 LPGTLMLTDCLEACQSNESCSAVNYETGLCVLFKTTADKLP--GSLSRSQFPVFTIYAQKSCLGV 201
            ||.:  .|.|..:|... :|:.|.::...|::.    ||..  |.:....      |.:|.|:..
 Worm    44 LPAS--ATACFNSCALG-NCTGVLFQGDKCIVI----DKSNYFGRIEERN------YIEKKCVKK 95

  Fly   202 RP---CSKAWCIDRVQGYRLPEHVKSSQTVL---SRRDCLELCLGETEFTCRSANYYRHSGLCEL 260
            .|   ..|.| .||:.       |..||:||   ::.:||.||..|..|.|.||.:||.|..|.|
 Worm    96 APHRLLVKEW-DDRIL-------VDKSQSVLKAETKLECLSLCAQEKRFPCLSAMFYRDSKDCLL 152

  Fly   261 ----SDMDRITLSAGGSVEPY---------------------------------DGADYLENNCA 288
                |...::.:..||....|                                 :|:|.| ..|.
 Worm   153 NSASSSSAKLKMDTGGFKVSYMELHGLKEAVHCLNAFKMVAFDAIEIRGESRIFNGSDGL-GKCM 216

  Fly   289 EEPSKLCE--------------FKRISGKILKTVDSVYQ-------------------------- 313
            |: .|.|:              :...||::|..|:..||
 Worm   217 EK-CKDCDVVMYNEGFSECYSVWNDPSGQLLDFVNDEYQILTNACSYQKKTCNSRNSLYISYSNP 280

  Fly   314 ------------------------------------------------DINTID----------- 319
                                                            |:|.:.
 Worm   281 DESLKSECLEKCTMSEECRFAYQSKDMNNCLISRRRMALPMLAQKICADVNDLSDGSAILFDELG 345

  Fly   320 -----------------ECRDLCLNSPYR-CHSYDYNDTGDMVCRLSHHSRATLTD--------- 357
                             :|..||...|.| |.|..|..:.|  |.|  |..|..||
 Worm   346 GCKNENGQLISKDLELHQCMQLCATHPTRSCESISYTKSRD--CYL--HDGAVETDNENTNCSVF 406

  Fly   358 ----------------------VMDPYLDVPEAATY-----------ELSACY------------ 377
                                  |..|:    :|.|:           |....|
 Worm   407 TLNVITFEQELKPTTIAPGDSKVKKPH----KAKTFSTGNKKDQKKVEERKLYVKKSSKLGSSPL 467

  Fly   378 --NVSIECRSGEMITKIR-----TSKLFDGKVYAKGAPKSCAVNVNNSLEFDFRMGYNDLECNVR 435
              .:|.:|..|.:..|:.     ...|..|::|.:....:|:..:....|...::.:||..|..:
 Worm   468 DVKISTQCTFGFISVKVSPGNPDNHNLVGGEIYVRNGHSNCSKTIGTDGEAILKIRHNDTTCITK 532

  Fly   436 QSAYGRYMNDIVIQHHDM-------IVTSSDLGLAVSCQYDLTNKTVLNDVDLGVTGEIESSLSE 493
            .   |.....:|:...::       ::|..|....|.|.|  :|:.  |.|.:..|..:.::...
 Worm   533 N---GDIYETVVVVTQNVESVGNATVITIDDQLFKVRCDY--SNQK--NAVAVAKTMNLRTTQFN 590

  Fly   494 EITI-DSPNV---IMKITSRDGSDMKRMAEVGDPLALRFEIVEPNSPYEIFVRELVAMDGSDSAE 554
            ::.| ...||   .|::..:......|..::|..|.|.|.:....|...:||::..|.|.:...:
 Worm   591 KLDIYGKVNVKPMSMELRGKREIIKARTVKLGQSLDLVFTVDNSTSARHVFVKKCTAYDQNGDEK 655

  Fly   555 ITLIDANGCPTD---QYIMGTIQKLAQNRKVLLSQFDAFKFPSSEVVQFRALVTPCIPRCEPVIC 616
            |.|| .|||.|.   :|::.  .::.:.....:..|.||:|...|.|:....|..| .:|:...|
 Worm   656 IILI-KNGCATQHAKEYVLR--DEIKETATGFVLPFRAFRFKQGEAVKIECEVKYC-EKCKKANC 716

  Fly   617 DSEDGASGELKSLVSYGRKKRSVLNGTDG-----AEFLIST 652
            .|.:      :...::...:.:.|.|.:.     ||.|:.|
 Worm   717 PSRN------RRFTTFDESEDTTLTGNEDTEKVHAELLVQT 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nyo	NP_651871.2	PAN_1	121..198	CDD:459635	13/60 (22%)
		PAN_AP_HGF	208..286	CDD:238532	29/117 (25%)
		PAN_1	295..358	CDD:459635	24/210 (11%)
		ZP	382..618	CDD:214579	54/254 (21%)
cutl-18	NP_505875.2	PAN_AP_HGF	105..177	CDD:238532	26/79 (33%)
		PAN_AP	187..258	CDD:214680	13/72 (18%)
		ZP	474..719	CDD:214579	54/255 (21%)