Protein Alignment nyo and cut-6

DIOPT Version :10

• Sequence 1: NP_651871.2
• Gene: nyo / 43716
• FlyBaseID: FBgn0039852
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: NP_499400.2
• Gene: cut-6 / 176520
• WormBaseID: WBGene00000853
• Length: 572
• Species: Caenorhabditis elegans
• Alignment Length: 515
• Identity: 112/515 - (21%)
• Similarity: 181/515 - (35%)
• Gaps: 125/515 - (24%)

  Fly   235 LELCLG------ETEFTCRSANYYRHSGLCELSDMDRITLSAGGSVEPYDGA------------D 281
            ||..||      :.|:..:...|  .||........|:||..|     ..||            |
 Worm    97 LEFSLGQFNHPTQLEWAIQRIEY--QSGATNTGQALRLTLEKG-----LQGARPGIPKVAIVITD 154

  Fly   282 YLENNCAEEPSKLCEFKRISGKILKTVDSVYQDINTIDECRDLCLNSPYRCHSYDYNDTGDMVCR 346
            ....:...|||:|          |:..|.:...|...:      |.:.::.|..    ||:.|
 Worm   155 GQSQDDVSEPSQL----------LRDADVMVYAIGVTN------LVNVHQLHQM----TGNPV-- 197

  Fly   347 LSHHSRATLTDVMDPYLDVPEAATYELSACYNVSIECRSG--EMI-------TKIRTSKLFDGKV 402
                 |....:..: .||...|.:...|.|   ..|.|.|  |:|       .|..|.:.|:|.|
 Worm   198 -----RVFTVESFE-QLDRALADSLTWSMC---KTEFRPGTPEIICGPDRIGVKASTKQPFEGNV 253

  Fly   403 Y---------AKGAPKSCAVNVNNSLEFDFRMGYNDLECNVRQSAYGRYMN--------DIVIQH 450
            :         .:..|:....:.:..|...|.      .|||.:.   |.:|        .||...
 Worm   254 FVMDHYHDEECRAGPEKFPDSRSIGLTVPFS------ACNVHRY---RSLNPKGIFVEVSIVFMF 309

  Fly   451 HDMIVTSSDLGLAVSCQYDLTNKTVLNDVDLGVTGEIESSLSEEITIDSPNVIMKITSRDGS--- 512
            |.:.:|.:|..:.|.|.|...:|.|  .|.|.|: .|.:...|:| ...|.  ...|.|.|:
 Worm   310 HSLFMTKTDQTVKVQCFYMEADKHV--TVPLSVS-MITTVFREQI-YQMPQ--CAYTLRKGAPDG 368

  Fly   513 DMKRMAEVGDPLALRFEIVE----PNSPYEIFVRELVAMDGSDSAEITLIDANGCPTDQYIMGTI 573
            .:.|.|.:|:.:..|:|.:|    ....:.:.|.... :|......:.::|:|||..|..::.|
 Worm   369 PIVRFATLGESVYHRWECIEVEGADKDTFGMLVHSCY-VDNGYGDRVDILDSNGCGLDAVLLST- 431

  Fly   574 QKLAQNRKVLLSQFDAFKFPSSEVVQFRALVTPCIP---RCE----PVICDSEDGASGELKSLVS 631
            .....:.::....:..||:....|:||:..:|.|:.   .||    |..|....|..|.......
 Worm   432 PDYDTSLRLATKPYHVFKYADRPVLQFQCQITLCLKYDGGCEGITPPQNCKKLPGEDGHHHHHHP 496

  Fly   632 YGRKK--RSVLNG-------TDGAEFLISTRHRRDVGP---VDDNILLMQSIQITDKFGF 679
            ..|:|  |.:.:|       ||....|......:...|   ::.|:.:|..|.:|:.|.|
 Worm   497 EKRRKLVRRLADGVGTIDVFTDSVTVLEQEPACQQPLPYPLINTNLWIMGIITLTNIFVF 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nyo	NP_651871.2	PAN_1	121..198	CDD:459635
		PAN_AP_HGF	208..286	CDD:238532	15/68 (22%)
		PAN_1	295..358	CDD:459635	9/62 (15%)
		ZP	382..618	CDD:214579	63/275 (23%)
cut-6	NP_499400.2	VWA	47..208	CDD:459670	28/145 (19%)
		ZP	233..480	CDD:214579	58/263 (22%)