DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mey and qsm

DIOPT Version :9

Sequence 1:	NP_001287622.1	Gene:	mey / 43715	FlyBaseID:	FBgn0039851	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_001286637.1	Gene:	qsm / 47065	FlyBaseID:	FBgn0028622	Length:	414	Species:	Drosophila melanogaster

Alignment Length:	434	Identity:	95/434 - (21%)
Similarity:	161/434 - (37%)	Gaps:	130/434 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   368 LVCRLSHHSRATLTDLSEPYLSIE----EAATYEQSACYNVSIDCRSGEMITKIRTSKLFDGKVY 428
            |.|.|:....:.....||..:.::    :|.:.:|||                        .::|
  Fly    16 LFCGLAQAKGSHKVHCSEDQMRVDIGLPDAESKDQSA------------------------PQIY 56

  Fly   429 ---AKGAP-KSCAVNVNNSLEFDLKMRYNDL-ECNVRQSAYGRYMNDIV---IQHHDMIV--TSS 483
               .||.| :.|...::.||.. .::..:|. ||.|.     |.:|.:.   :.:|.:|:  ||.
  Fly    57 LEGLKGYPDERCQPQIDGSLAV-FRLSLSDFYECGVT-----RMVNQLTGKKVYYHKIIIESTSG 115

  Fly   484 DLGLAVSCQYDLTNKTVVNNVDLGVT----------GEIESTLSEEII------VDSPNVIMKIT 532
            ...::|.|   :|..:...||.:..|          |.|...:..:::      .:...:...:|
  Fly   116 KEIVSVKC---ITTASPAYNVMMNATTGSSSTSTSSGGIHGLVKRDVLPAGFQEPEDLEITTSLT 177

  Fly   533 AR------------DGSDMKRIAEV--GDPLALRFEIVDANSP-YEIFVRELVAMDGTDSAEITL 582
            .|            ||....|...|  |.||.:...:.:.::| |.:.|..|...|...|:| ||
  Fly   178 KRAPEPRLSIGVSQDGQKFTRDLTVKSGTPLTMEINLDEDSAPVYGLGVNYLDVTDTHTSSE-TL 241

  Fly   583 IDANGCPTDQYIMSAMQKLANNRKVLLSQFDAFKFPSSELVQFRALVTPCIPRCEPVICDNDENG 647
            | ..||..|.|:......:..:  :|.::|.|||||.|..|||||.|..|:.:|....|.|::.|
  Fly   242 I-FKGCTVDPYLFENFNTIDGD--ILSAKFKAFKFPDSSYVQFRATVNVCLDKCLGTQCSNNQVG 303

  Fly   648 ELKSLLSYGRRKRSVLNGTDGVELAIKSERQKRDVSHQAAGDENILLVQSIQITDK--------- 703
                   :|||||.:.:.....|:::....|.:|:       |.:...:.:|:.:|
  Fly   304 -------FGRRKREISSANKVYEISLAMFLQVQDI-------EGVNKNEVLQLEEKLRELKLANQ 354

  Fly   704 ---------FAFNGADA----------------PGGSGSEAGGL 722
                     ||.....|                ..|||:.:.||
  Fly   355 RLARNSRGNFAMEQTPASAQPAFVVDERELGHLSAGSGAASNGL 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mey	NP_001287622.1	PAN_1	146..223	CDD:278453
		PAN_AP_HGF	233..311	CDD:238532
		PAN_AP_HGF	319..>380	CDD:238532	3/11 (27%)
		ZP	408..642	CDD:214579	64/274 (23%)
qsm	NP_001286637.1	ZP	30..298	CDD:214579	70/304 (23%)
qsm	NP_001286637.1	Zona_pellucida	<200..300	CDD:278526	35/103 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JEZ
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910