DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mey and CG17111

DIOPT Version :9

Sequence 1:	NP_001287622.1	Gene:	mey / 43715	FlyBaseID:	FBgn0039851	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_651119.2	Gene:	CG17111 / 42727	FlyBaseID:	FBgn0039048	Length:	792	Species:	Drosophila melanogaster

Alignment Length:	694	Identity:	164/694 - (23%)
Similarity:	265/694 - (38%)	Gaps:	148/694 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 CLEACQANESCSAVNY--ETGLC---VMFRSTADQLPGSLSRSQYPVF----TVYAQKSCFGVRP 228
            |...|..:..|.|..:  :|..|   ..|..|:..|..|   .:.|:.    .|:.:|:|..|..
  Fly    87 CWRICNEDPDCIAYVHLLDTDECHGYSYFERTSRYLAIS---GELPLVADGEAVFYEKTCLRVPD 148

  Fly   229 C--SKAWCIDRVQGYRLPERAKAS-QSVATRRDCIELCLGETEFTCRSANY---YAHS------- 280
            .  .:.|.:.::.|..|...:|.: .::.|||:|.|.|..||:|.|.||::   |.::
  Fly   149 ACRGRLWALTKIPGSTLVYHSKKTISTLVTRRECAERCFFETQFRCLSASFAPSYRNNRERFRGE 213

  Fly   281 -----------GLCELSDMDRITLSDEANIAAYDGADYLENNCAEE--PSKLCEFKRVAGRILKT 332
                       |.|.|||.|:....|....|.|| .:|:||.|.|.  .|..|.::..|......
  Fly   214 AGPGQRPSPRLGRCMLSDRDKTVQPDAFRAAPYD-EEYMENQCHERAIESDNCSYELYANSSFIY 277

  Fly   333 VDSVHQNVQTLDECRDLCL-TAPFRCHS---YDYNETGELVCRLSHHSRATLTDLSEPYLSIEEA 393
            .::.:..: :..||:.:|. .|.|.|..   |..|:.....|.|  ||. .:..|....|.:.|.
  Fly   278 AEARYLGL-SQKECQAMCSHEAKFYCQGVSFYYVNQLSLSECLL--HSE-DIVSLGPRSLKLREN 338

  Fly   394 ATY-EQSACYNVSIDCRSGEMITKIRTSKLFDGKVYAKGAPKSCAV--NVNNSLEFDLKM--RYN 453
            :.| .:..|.:|.:.|...||..|......|.||:||....|.|..  :.|.|:...|::  ...
  Fly   339 SVYMRRVKCLDVRVFCTRDEMTIKYNPKDWFVGKIYASMHSKDCLARGSGNGSVLLTLQIGSEVK 403

  Fly   454 DLECNVRQS-----AYGRYMND--IVIQHHDMIVTSSDLGLAVSC-QYDLTNKTVVNNVDLGVTG 510
            :..|.:.::     .|.|....  :|||::..:.|..|..:.|.| |.:.|....|:..|..|..
  Fly   404 ENRCGILRAYEMTQEYQRTFISALVVIQNNPNVQTQGDRLIKVGCIQSNATTSLGVSVRDSSVDS 468

  Fly   511 E--------IESTLS-------EEIIV---------DSPNVIMKITARDGSDMKRIAEVGDPLAL 551
            .        :||:|.       .|.:|         ..|::.::|............::|..|.|
  Fly   469 SEPVPSAIALESSLEYTEHMFPHEGVVHYNSSTGPHPHPSISLQILDLSHQHETNDVQIGQNLEL 533

  Fly   552 RFEIVDANSPYEIF--------------VRELVAMDGTDSAEITLIDANGCPTDQYIMSAMQKL- 601
              :||...||.::.              ...|||....:...:.|||..|||||..:..|::::
  Fly   534 --QIVAEYSPQQLAEHMELQLAPLPDFRATSLVAKTADNENFVLLIDERGCPTDASVFPALERVH 596

  Fly   602 ANNRKVLLSQFDAFKFPSSELVQFRALVTPCIPRCEPVICDNDENGELKSLLSYGRRKRSVLNGT 666
            ..:|.:|.::|.||||..:..|.|...:..|:.||.|..|.:.         |:.||:|.
  Fly   597 TASRSMLRARFHAFKFSGTANVSFDVKIRFCVERCSPSNCISS---------SWQRRRRQ----- 647

  Fly   667 DGVELAIKSERQKRDVSHQ-----------AAGDENILLVQ-SIQITDKFAFNGADAPGGSG--- 716
                 |.:.:|:..|:..|           |...:|....| .:.:......:|.|....:.
  Fly   648 -----ADQPDRRPEDLRVQNPVYISTVVDVAPQPDNFTRSQEELPLNYNIRVHGPDQSNTNSYLY 707

  Fly   717 SEAG-----GLDGLAKLQLDLGTKSDTCINGYGFIIAGALFLLL 755
            .|.|     |:|.  .|.||     :.||| ...:||..:|.|:
  Fly   708 GERGVLLIAGIDD--PLHLD-----NVCIN-QSLLIALFIFWLI 743

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mey	NP_001287622.1	PAN_1	146..223	CDD:278453	13/58 (22%)
		PAN_AP_HGF	233..311	CDD:238532	29/99 (29%)
		PAN_AP_HGF	319..>380	CDD:238532	14/64 (22%)
		ZP	408..642	CDD:214579	68/284 (24%)
CG17111	NP_651119.2	PAN_1	159..255	CDD:278453	29/96 (30%)
CG17111	NP_651119.2	PAN_AP_HGF	270..344	CDD:238532	17/77 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JEZ
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12391
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005301
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.860