Protein Alignment mey and cutl-28

DIOPT Version :9

• Sequence 1: NP_001287622.1
• Gene: mey / 43715
• FlyBaseID: FBgn0039851
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_499971.2
• Gene: cutl-28 / 176895
• WormBaseID: WBGene00018256
• Length: 696
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 145/599 - (24%)
• Similarity: 244/599 - (40%)
• Gaps: 112/599 - (18%)

  Fly   161 LETLPGTL----------------------------MLTDCLEACQANESCSAVNYETGLCVMFR 197
            |.|||.|:                            .|:.|...|.:..:|:...:
 Worm    11 LSTLPSTVSPCEITFILETLKSVNSTASLIIRKSVDSLSQCTRFCSSVPNCTHFTF--------- 66

  Fly   198 STADQLP---GSLS---RSQYPVFTVYAQKSCFGVRPCSKAWCIDRVQGY-RLPERAKASQSVAT 255
            |.|:.:.   |..:   .|:.||.|....:: .|.:.|.:..|:.|...: :.|.|:..:.|...
 Worm    67 SNAEPIEKKNGGFNCHLHSKSPVLTTSGSRT-VGTKTCLENKCLKRSFAFEKFPGRSLVNSSFII 130

  Fly   256 R------RDCIELCLGETEFTCRSANYYAHSGLCELSDMDRITLSDEANIAAYDGADY----LEN 310
            :      .:|:..|  :.|.:||:|.:...:.||:||   |::|:...|...|..|.|    .||
 Worm   131 KTFSISMEECLSQC--QKESSCRAALHNNDTSLCQLS---RVSLNSVYNPRLYFKASYSVDLYEN 190

  Fly   311 NCAE--EPSKLCEFKRVAGRILKTV-DSVHQNVQTLDECRDLCLTAPFR------CHSYDY-NET 365
            ||.:  ..|..|.|.||.|..||:| |.:.|||.:.|||..:|:   .|      |.||.| |.|
 Worm   191 NCVDYAMTSSACTFMRVNGGGLKSVSDQLIQNVGSFDECEQMCV---IRSRISDVCRSYTYDNST 252

  Fly   366 GELVCRLSHHSRATLTDLSEPYLSIEEAATY-EQSACYNVSIDCRSGEMITKIRTSKLFDGKVYA 429
            .|  |.|...|...|.  ..|..|::....: :...|.|.|:.||...:..|..:.::|.||:..
 Worm   253 NE--CNLMWASARMLG--RSPLESMKPNLFHGDLDDCVNFSLKCREDNLEVKASSMRMFIGKMMT 313

  Fly   430 KGAPK-SCAVNVNNSLEFDLKMRYNDLECNVRQSAYGRYMNDI-VIQHHDMIVTSSDLGLAVSCQ 492
            |.:.| .|..:...:.:|..|..:.....:..:|....|...: |.:....:||..|..|.|:|:
 Worm   314 KKSKKIMCQEDYEGNYDFSSKFDFKKCGLDPNKSKDSTYRGMVHVKEGSTSLVTIRDKVLQVNCR 378

  Fly   493 Y--DLTNKTVVNNVDLGV--TGEIESTLSEEIIV------DSPNVIMKITARDGSDMKRIAEVGD 547
            .  .:.::....:|.:.|  ..:....:|:.::|      .:|...:||...|.::...: .:||
 Worm   379 LHKSMPSEEQFLSVQMNVRENNKTNQVMSDVVVVTAPPAQTNPKFSLKILGLDSTEADTV-HIGD 442

  Fly   548 ----PLALRFEIVDANSPYEIFVRELVAMDGTDSAEITLIDANGCPTDQYIMSAMQKLANNRKVL 608
                .||::      ||..:..|..|||.|......:.:||.:||...:.|:..::|..|..|:.
 Worm   443 YGWIMLAVK------NSAEDFTVTNLVAKDVQTGRVLRIIDEDGCVLRRDIVKEIRKTDNYVKLK 501

  Fly   609 LSQFDAFKFPSSELVQFRALVT---PCIPRCEPVICDNDENGELKSL-----LSYGRRKRSVLNG 665
            :| |..|: ..:|:|....:.|   .|:|:|...:...:|...:.||     |...|..|..|.|
 Worm   502 IS-FSGFR-RQTEVVYHAMMETCTVGCMPKCNQDMMLPEEETNVHSLPLSLDLPRHRMVRRSLAG 564

  Fly   666 TDGVELAIKSERQK 679
             :..||.:.|:..|
 Worm   565 -EPRELQLTSDVYK 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mey	NP_001287622.1	PAN_1	146..223	CDD:278453	16/95 (17%)
		PAN_AP_HGF	233..311	CDD:238532	22/88 (25%)
		PAN_AP_HGF	319..>380	CDD:238532	27/68 (40%)
		ZP	408..642	CDD:214579	56/252 (22%)
cutl-28	NP_499971.2	APPLE	30..103	CDD:128519	12/82 (15%)
		PAN_1	114..192	CDD:278453	21/82 (26%)
		PAN_1	202..292	CDD:278453	33/96 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JEZ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	106	1.000	Inparanoid score	I3502
Isobase	1	0.950	-	0	Normalized mean entropy	S12391
OMA	1	1.010	-	-		QHG28931
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto19562
orthoMCL	1	0.900	-	-		OOG6_115610
Panther	1	1.100	-	-	O	PTHR47327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.780