DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11333 and ISOC1

DIOPT Version :9

Sequence 1:	NP_651869.1	Gene:	CG11333 / 43714	FlyBaseID:	FBgn0039850	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_057132.2	Gene:	ISOC1 / 51015	HGNCID:	24254	Length:	298	Species:	Homo sapiens

Alignment Length:	182	Identity:	80/182 - (43%)
Similarity:	117/182 - (64%)	Gaps:	2/182 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LYRLVPSKTLFMLCDVQEKFKPAIPLLSSLIENTTKLLAAGKVFQVPLLVTEQYPERLGKTVCEL 73
            |..|.||.|:|..||:||:|:|||.....:|....:||...::..:|::||||||:.||.||.|:
Human   107 LGNLTPSSTVFFCCDMQERFRPAIKYFGDIISVGQRLLQGARILGIPVIVTEQYPKGLGSTVQEI 171

  Fly    74 DIKHACANISKTMFSMLVEPVRKSMTDIFGGKPKTVVLFGLETHVCVEQTAFDLVNDEIDVWLVA 138
            |:......:.||.|||::..|..::.:|.|  .::|||||:|||||::|||.:||...::|.:||
Human   172 DLTGVKLVLPKTKFSMVLPEVEAALAEIPG--VRSVVLFGVETHVCIQQTALELVGRGVEVHIVA 234

  Fly   139 DCCASRHNQDRDLALERLRHIGCNIATSESVIFNLLGDKNNKSFKEITPLVK 190
            |..:||...||..|||||...|..:.|||:|:..|:.||::..||||..|:|
Human   235 DATSSRSMMDRMFALERLARTGIIVTTSEAVLLQLVADKDHPKFKEIQNLIK 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11333	NP_651869.1	YcaC_related	18..175	CDD:238494	67/156 (43%)
ISOC1	NP_057132.2	YcaC_related	116..270	CDD:238494	66/155 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143761
Domainoid	1	1.000	140	1.000	Domainoid score	I4758
eggNOG	1	0.900	-	-		E1_COG1335
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4185
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54144
OrthoDB	1	1.010	-	-		D1100720at2759
OrthoFinder	1	1.000	-	-		FOG0001690
OrthoInspector	1	1.000	-	-		mtm8500
orthoMCL	1	0.900	-	-		OOG6_101675
Panther	1	1.100	-	-	O	PTHR14119
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1084
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.770