DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Loxl1 and Marco

DIOPT Version :9

Sequence 1:	NP_524607.1	Gene:	Loxl1 / 43712	FlyBaseID:	FBgn0039848	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_034896.1	Gene:	Marco / 17167	MGIID:	1309998	Length:	518	Species:	Mus musculus

Alignment Length:	124	Identity:	37/124 - (29%)
Similarity:	52/124 - (41%)	Gaps:	30/124 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 NYRNMMVRLATNKAALAGIQVLREGRVEVSFDFGASWGTICSTSWSMREANVVCRQLGLGYASKA 91
            :::.:.:...||:           ||.||.::  ..|||||...|...:|.|.||.||.   |:.
Mouse   419 SFQRVRIMGGTNR-----------GRAEVYYN--NEWGTICDDDWDNNDATVFCRMLGY---SRG 467

  Fly    92 SQGTEHGDSRKYPWGMVGTLCRGTERRLADCIRESHYPNLCNARNHNVSIAACVSHSAD 150
            ...:.:|......| :....|||||..|.||.:.|.       .|||     || |:.|
Mouse   468 RALSSYGGGSGNIW-LDNVNCRGTENSLWDCSKNSW-------GNHN-----CV-HNED 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Loxl1	NP_524607.1	SRCR	50..137	CDD:278931	28/86 (33%)
		SR	50..136	CDD:214555	28/85 (33%)
		Lysyl_oxidase	149..343	CDD:279521	1/2 (50%)
Marco	NP_034896.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	147..426		0/6 (0%)
		Collagen	150..207	CDD:189968
		Collagen	192..249	CDD:189968
		Collagen	264..323	CDD:189968
		Collagen	360..418	CDD:189968
		SR	423..518	CDD:214555	37/120 (31%)
		SRCR	428..518	CDD:278931	37/115 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000389
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000