DRSC/TRiP Functional Genomics Resources

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Protein Alignment Loxl1 and Loxl3

DIOPT Version :9

Sequence 1:NP_524607.1 Gene:Loxl1 / 43712 FlyBaseID:FBgn0039848 Length:360 Species:Drosophila melanogaster
Sequence 2:NP_038614.2 Gene:Loxl3 / 16950 MGIID:1337004 Length:754 Species:Mus musculus


Alignment Length:324 Identity:133/324 - (41%)
Similarity:175/324 - (54%) Gaps:23/324 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 KAALAGIQVLREGRVEVSFDFGA--SWGTICSTSWSMREANVVCRQLGLGYASKASQGTEHGDSR 101
            |..|:|.:...||||||......  .||.||...|...||.|.|||||||||:...|.|.:.|| 
Mouse   417 KIRLSGGRSRYEGRVEVQIGIPGHLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDS- 480

  Fly   102 KYPWG------MVGTLCRGTERRLADCIRESHYPNLCNARNHNVSIAACVSHSADLEIGLVDIER 160
                |      |.|..|.|:|..|..|...|.:...........:...|...::||.:....::.
Mouse   481 ----GNVTEVVMSGVRCTGSELSLNQCAHHSSHITCKKTGTRFTAGVICSETASDLLLHSALVQE 541

  Fly   161 TARLEAVPMSRLTCAMEEHCVSADAYEIRRTN-PHAARILLRFSVKASNVGTADVSPYANYKEWV 224
            ||.:|..|:..|.||.||:|:::.|   |..| |:..|.|||||.:..|:|.||..|.|....||
Mouse   542 TAYIEDRPLHMLYCAAEENCLASSA---RSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWV 603

  Fly   225 WHQCHRHYHSMNVFATFDVYDLNYRKVAQGHKASFCLMDSECRPGVRQKYTCGN-TTQGISVGCA 288
            ||:||.|||||::|..:|:...|..|||:||||||||.|:||:..|.::|.|.| ..|||:|||.
Mouse   604 WHECHGHYHSMDIFTHYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCW 668

  Fly   289 DTYTDVLDCQWVDVTRV-PINRRYILRVALNPEYKLGEISFENNGAECLLDYTGVRQTTRIFNC 351
            |.|...:||||:|:|.| |.|  |||:|.:||.:::.|..|.||..:|...|.|.|  ..:.||
Mouse   669 DLYRHDIDCQWIDITDVKPGN--YILQVVINPNFEVAESDFTNNAMKCNCKYDGHR--IWVHNC 728

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Loxl1NP_524607.1 SRCR 50..137 CDD:278931 36/94 (38%)
SR 50..136 CDD:214555 36/93 (39%)
Lysyl_oxidase 149..343 CDD:279521 90/196 (46%)
Loxl3NP_038614.2 SR 46..145 CDD:214555
SRCR 54..146 CDD:278931
SR 170..282 CDD:214555
SRCR 187..282 CDD:278931
SR 308..408 CDD:214555
SRCR 313..408 CDD:278931
SR 418..526 CDD:214555 38/112 (34%)
SRCR 423..526 CDD:278931 36/107 (34%)
Lysyl-oxidase like 530..733 93/206 (45%)
Lysyl_oxidase 531..725 CDD:279521 91/200 (46%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_28KG1
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000389
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45817
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
65.870

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