DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Loxl1 and loxl3

DIOPT Version :9

Sequence 1:	NP_524607.1	Gene:	Loxl1 / 43712	FlyBaseID:	FBgn0039848	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_031751060.1	Gene:	loxl3 / 101733365	XenbaseID:	XB-GENE-5825439	Length:	788	Species:	Xenopus tropicalis

Alignment Length:	318	Identity:	135/318 - (42%)
Similarity:	179/318 - (56%)	Gaps:	18/318 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LAGIQVLREGRVEVSF--DFGASWGTICSTSWSMREANVVCRQLGLGYASKASQGTEHGD-SRKY 103
            |.|.:...||||||.:  .....||.:|...|.:.||..||:||||||||.:.|.|.:.| |...
Frog   455 LFGGRTRYEGRVEVLWGPPEAKRWGLVCGQGWGILEAATVCQQLGLGYASSSLQETWYWDASNAT 519

  Fly   104 PWGMVGTLCRGTERRLADCIRESHYPNL-C-NARNHNVSIAACVSHSADLEIGLVDIERTARLEA 166
            ...:.|..|.|||..|..|   .|:.:: | |....:.:...|...::||.:....::.||.:|.
Frog   520 EMVLSGVRCTGTEMSLGQC---GHHTSVSCKNTGTRHAAGVICSETASDLVLHSALVQETAYIED 581

  Fly   167 VPMSRLTCAMEEHCVSADAYEIRRTN-PHAARILLRFSVKASNVGTADVSPYANYKEWVWHQCHR 230
            .|:..|.||.||:|:|:.|   |..| |:..|.|||||.:..|.|.||..|.|....||||:||.
Frog   582 RPLHMLYCAAEENCLSSSA---RHANWPYGHRRLLRFSSQIHNNGRADFRPKAGRHSWVWHECHG 643

  Fly   231 HYHSMNVFATFDVYDLNYRKVAQGHKASFCLMDSECRPGVRQKYTCGN-TTQGISVGCADTYTDV 294
            |||||::|..:|:...|..|||:||||||||.||||:..|.::|.|.| ..|||:|||.|.|...
Frog   644 HYHSMDIFTHYDLLTPNGTKVAEGHKASFCLEDSECQELVSKRYECANFGEQGITVGCWDLYRHD 708

  Fly   295 LDCQWVDVTRV-PINRRYILRVALNPEYKLGEISFENNGAECLLDYTGVRQTTRIFNC 351
            :||||:|:|.| |.|  |||:|.:||.:::.|..|.||..:|...|.|.|  ..|.||
Frog   709 IDCQWIDITDVKPGN--YILQVVINPNFEVAESDFTNNAMKCNCKYDGHR--IWIHNC 762

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Loxl1	NP_524607.1	SRCR	50..137	CDD:278931	36/91 (40%)
		SR	50..136	CDD:214555	36/90 (40%)
		Lysyl_oxidase	149..343	CDD:279521	92/196 (47%)
loxl3	XP_031751060.1	SR	41..140	CDD:214555
		SR	180..316	CDD:214555
		SR	343..443	CDD:214555
		SR	453..560	CDD:214555	38/107 (36%)
		Lysyl_oxidase	565..764	CDD:395944	96/205 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000389
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000