DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Loxl1 and Gm21451

DIOPT Version :9

Sequence 1:	NP_524607.1	Gene:	Loxl1 / 43712	FlyBaseID:	FBgn0039848	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_006519955.1	Gene:	Gm21451 / 100862072	MGIID:	5434806	Length:	748	Species:	Mus musculus

Alignment Length:	285	Identity:	125/285 - (43%)
Similarity:	156/285 - (54%)	Gaps:	32/285 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 KAALAGIQVLREGRVEVSFDFGAS--WGTICSTSWSMREANVVCRQLGLGYASKASQGT--EHGD 99
            |..|.|.:...||||||..:...|  |||:|..:|.:.||.|||||||||:||.|.|.|  .||:
Mouse   444 KVRLNGGRNPYEGRVEVLTERNGSLVWGTVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGN 508

  Fly   100 SRKYPWGMVGTLCRGTERRLADCIRESHYPNLCNARNHNVSIA------------ACVSHSADLE 152
            .......|.|..|.|||..||.|             .|:..:|            ||...:.||.
Mouse   509 IFANNVVMSGVKCSGTELSLAHC-------------RHDEEVACPEGGVRFGAGVACSETAPDLV 560

  Fly   153 IGLVDIERTARLEAVPMSRLTCAMEEHCVSADAYEIRRTNPHAARILLRFSVKASNVGTADVSPY 217
            :....:::||.||..|||.|.|||||:|:||.|.....|..|  |.|||||.:..|.|.:|..|.
Mouse   561 LNAEIVQQTAYLEDRPMSLLQCAMEENCLSASAVHTDPTRGH--RRLLRFSSQIHNNGQSDFRPK 623

  Fly   218 ANYKEWVWHQCHRHYHSMNVFATFDVYDLNYRKVAQGHKASFCLMDSECRPGVRQKYTCGN-TTQ 281
            .....|:||.||||||||.||..:|:..||..|||:||||||||.|:||...:::.|.|.| ..|
Mouse   624 NGRHAWIWHDCHRHYHSMEVFTYYDLLSLNGTKVAEGHKASFCLEDTECEGDIQKSYECANFGEQ 688

  Fly   282 GISVGCADTYTDVLDCQWVDVTRVP 306
            ||::||.|.|...:||||:|:|.||
Mouse   689 GITMGCWDMYRHDIDCQWIDITDVP 713

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Loxl1	NP_524607.1	SRCR	50..137	CDD:278931	39/90 (43%)
		SR	50..136	CDD:214555	39/89 (44%)
		Lysyl_oxidase	149..343	CDD:279521	79/159 (50%)
Gm21451	XP_006519955.1	SR	61..162	CDD:214555
		SR	204..304	CDD:214555
		SR	336..435	CDD:214555
		SR	445..553	CDD:214555	44/120 (37%)
		Lysyl_oxidase	557..721	CDD:366506	79/159 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D376277at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010