DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PNPase and AT5G14580

DIOPT Version :9

Sequence 1:	NP_001097990.2	Gene:	PNPase / 43710	FlyBaseID:	FBgn0039846	Length:	771	Species:	Drosophila melanogaster
Sequence 2:	NP_196962.1	Gene:	AT5G14580 / 831309	AraportID:	AT5G14580	Length:	991	Species:	Arabidopsis thaliana

Alignment Length:	797	Identity:	311/797 - (39%)
Similarity:	456/797 - (57%)	Gaps:	63/797 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAMIFTRKSLKLLNYRLKCLSLSCPG-------GRRGIQSSSNGEAPSV---------------E 43
            |:.|..|.|           |.|.|.       |.|.|.|...|.||||               :
plant     1 MSSIVNRAS-----------SASLPNFLAWRALGFRTICSGRLGFAPSVPDSPVSAGTKILESFK 54

  Fly    44 VNFSNG-RNMTFSSGRLARFANGTAVCQMGDTAVMVTAVAKAKPNPGQGFMPLVVDYRLKNAASG 107
            ..|..| |.::|.:|::||||||:.|..|.:|.|:.| |..||.:..:.|:||.|||:.|..|.|
plant    55 EEFEVGSRVVSFETGKIARFANGSVVLGMDETKVLST-VTCAKTDSPRDFLPLTVDYQEKQYAQG 118

  Fly   108 RIPMNFMRRELGPSEKEILSARLIDRSLRPLFHKDYRTETQLVCNMLAMDAVHSPDVLAINAASM 172
            .||..:||||..|.|:|:|..|||||.:||||...:..|.|::.::|:.|....||:||.||:|.
plant   119 LIPNTYMRREGAPKERELLCGRLIDRPIRPLFPTGFYHEVQIMASVLSSDGKQDPDILAANASSA 183

  Fly   173 ALSLSDIPWNGPIGAVRVGLCDGEVLINPTRRELQTSQLDLVVSATKQNLVVMLEGKGNVVLQQD 237
            ||.|||:||.||||.:|:|...|:.::|||..||.:|.|:|:.:.|:.. .:|::.:...:.::|
plant   184 ALMLSDVPWGGPIGVIRIGRICGQFVVNPTMDELSSSDLNLIYACTRDK-TMMIDVQSREISEKD 247

  Fly   238 LLKAIKQGTREA-QFIIHEIERLQKAYGRQKREVEVAAEVDPELGKAVRSMCEMRLREIFQDSTH 301
            |..|::....|| :::..:|...:|| |:||:|.:::...|..|.| |..:...|:..:|.|.::
plant   248 LAAALRLAHPEAVKYLDPQIRLAEKA-GKQKKEYKLSMLSDKTLEK-VADLAATRIESVFTDPSY 310

  Fly   302 DKMSRDNAVNEVRSNVIDKVWSSFPDTEP-SLITEQFNQTSRTIFRELIFERGLRCDGRDYDQLR 365
            .|..|..|::.:..:| .||:....|.|. |::.:..:...:.:.|..:...|.|.|||..|::|
plant   311 GKFERGEALDNIGKDV-RKVFEEEGDQESLSILPKAVDTVRKKVVRSRMISDGFRVDGRHVDEVR 374

  Fly   366 NISCQVDMYKPLHGSALFQRGQTQVFCTVSLDSQESAMKLDSLAALDSGGLKAKNFMLHYEFPPY 430
            .|.|:......|||||||.||.|||.|||:|.:...|..||||.     |...|.|||||.||||
plant   375 PIYCESHYLPALHGSALFSRGDTQVLCTVTLGAPAEAQSLDSLV-----GPPKKRFMLHYSFPPY 434

  Fly   431 ATGEVGRIGPVGRREMGHGALAERSLLPTLPND--YPFTVRLTSEVLESNGSSSMASVCGGSLAL 493
            .|.|||:.|.:.|||:|||.|||::||..||.:  :|:|:|:.|||:.|:||:|||||||||:||
plant   435 CTNEVGKRGGLNRREVGHGTLAEKALLAVLPPEEAFPYTIRINSEVMSSDGSTSMASVCGGSMAL 499

  Fly   494 MDAGVPVSAPAAGVAIGLVTKFENDDTKHLQDYRILTDILGIEDYMGDMDMKVAGTRKGFTAIQA 558
            ||||:|:.|..|||::||:|..: ..:..::||||:|||||:||::||||.|:||||.|.||||.
plant   500 MDAGIPLRAHVAGVSVGLITDVD-PSSGEIKDYRIVTDILGLEDHLGDMDFKIAGTRDGVTAIQL 563

  Fly   559 DLKIPGIPLKVVMESLQKATDAKSNILDIMSEAIREPRKYPKESWPVSETLTVEPQQRAQLIGPS 623
            |:|..||||.:|.|||:.|.:|:..|||.|...|..||.......|...||.........||||.
plant   564 DIKPAGIPLDIVCESLENAREARLQILDHMERNINSPRGQDGAYSPRLATLKYSNDSLRTLIGPM 628

  Fly   624 GLHMKRIYLETGTSLTAVDETHFNVFAPSQAAMDEAKELIEGYMVKERVPDLEFGGIYTAKITEL 688
            |:..::|.:|||..| ::|.....:.|.:|..|::|:|.::..:.:|    |..||:|...::.:
plant   629 GVLKRKIEVETGARL-SIDNGTLTIVAKNQDVMEKAQEQVDFIIGRE----LVVGGVYKGTVSSI 688

  Fly   689 RDTGVMVILYPSMPPALLHNSQLDQRKIAHPSALNLEVGQEIQVKYFGRDPVSGFMRLSRKVLQG 753
            ::.|..| .:|.....|||.|:|....::..|.: |::||.|.......| |.|.::||||.|
plant   689 KEYGAFV-EFPGGQQGLLHMSELSHEPVSKVSDV-LDIGQCITTMCIETD-VRGNIKLSRKAL-- 748

  Fly   754 PALGIPRSLNKSAGESG 770
                :|:...|.|.::|
plant   749 ----LPKPKRKPASDAG 761

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PNPase	NP_001097990.2	PRK11824	42..751	CDD:236995	291/728 (40%)
AT5G14580	NP_196962.1	PRK11824	49..749	CDD:236995	291/724 (40%)
AT5G14580	NP_196962.1	RpsA	<651..977	CDD:223613	35/124 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	155	1.000	Domainoid score	I1346
eggNOG	1	0.900	-	-		E1_COG1185
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12404
Inparanoid	1	1.050	501	1.000	Inparanoid score	I316
OMA	1	1.010	-	-		QHG58167
OrthoDB	1	1.010	-	-		D236073at2759
OrthoFinder	1	1.000	-	-		FOG0005289
OrthoInspector	1	1.000	-	-		oto3693
orthoMCL	1	0.900	-	-		OOG6_102161
Panther	1	1.100	-	-	LDO	PTHR11252
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4288
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840