| Sequence 1: | NP_001263142.1 | Gene: | Gcn2 / 43709 | FlyBaseID: | FBgn0019990 | Length: | 1591 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_113787.1 | Gene: | Eif2ak3 / 29702 | RGDID: | 70884 | Length: | 1108 | Species: | Rattus norvegicus |
| Alignment Length: | 1089 | Identity: | 248/1089 - (22%) |
|---|---|---|---|
| Similarity: | 396/1089 - (36%) | Gaps: | 378/1089 - (34%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 145 DKQKRDQELQDIQRQRESLQRQTLIDEVERRKEMFKTEAKRRGEPRRSMSESNPRHPSSSESSEN 209
Fly 210 SSPYYRGH--IYPSK-------CLDHRNTETLYF---------HKMGRQIQRGCCVGEGHSQRGC 256
Fly 257 IAYTGIDMHCGQLLYI------TEWNIKYSQLEQ----------------PCIGGGKCHWS---- 295
Fly 296 ----------------SESKCMGSHRVDEVMASIEKQ----VSSLSQLQHKNLVSYECVLCIKRK 340
Fly 341 EGLLVYLVQDFLLGTSVFSISSSLGWCMDGARMVARGVLDALVFLHNKGVSHSH---------LL 396
Fly 397 DTTVFMDN-------TGNVRVSD-FSLVPNLLELLSGAGQSSSCGDLPAL--GALVESLMPTNSY 451
Fly 452 EMRDFVDKCNSDRTLSASE-------LLEHPFLRFYVDNG------------------------- 484
Fly 485 ------------------------------------QQQVMPLPQQQHPNTVQRTGSAMPYQIPT 513
Fly 514 LALSQ------------SRLRTEFEVLMYLGKGAFGDVLKVRNILDNREYAIKRIPLPARSRQLY 566
Fly 567 K-KMTREVELLSRLNHENVVRYFNSWIESVDDADAAEMDKLL----GGEW---SQSQQDL-SVK- 621
Fly 622 ----P----------AKSPQ--------------------------LGPTLEEDEDEEDSSSSMW 646
Fly 647 NGYIP--NMEDSDSDG---------------------------IEFVDS---------------- 666
Fly 667 -NG-----KVAVYDDEEQEDS---------TRGKT---------------NSPKPLMQVMYIQME 701
Fly 702 FCEKCTLRTAIDDNLFNDTDRLWR----LFREIAEGLAHIHQQGIIHRDLKPVNIFLDSHDQIKI 762
Fly 763 GDFGLATTSFLALQAHD-----AAPAPVNQITSAEDGTGTGKVGTTLYVAPE-LTGNASKSVYNQ 821
Fly 822 KVDMYTLGIILFEMCQPPFDTSMERAQTIMALRNVSINIPDAMLKDP-----KYEKTVKMLQWLL 881
Fly 882 NHDPAQRPTAEELLISDLVPPAQLEANEL--QEMLRHALANPQSKAYKN 928 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Gcn2 | NP_001263142.1 | RWD | 17..130 | CDD:214735 | |
| PK_eIF2AK_GCN2_rpt1 | 261..476 | CDD:270914 | 53/286 (19%) | ||
| STKc_EIF2AK4_GCN2_rpt2 | 518..898 | CDD:270948 | 152/531 (29%) | ||
| S_TKc | 525..895 | CDD:214567 | 149/509 (29%) | ||
| HisS | 974..1414 | CDD:223202 | |||
| class_II_aaRS-like_core | 974..>1137 | CDD:294192 | |||
| Eif2ak3 | NP_113787.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1080..1108 | 4/15 (27%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 71..92 | 3/12 (25%) | |||
| Luminal_EIF2AK3 | 99..412 | CDD:188874 | 61/344 (18%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 542..563 | 2/20 (10%) | |||
| PKc_like | 579..>667 | CDD:304357 | 39/89 (44%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 772..818 | 4/45 (9%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 832..856 | 4/23 (17%) | |||
| STKc_EIF2AK3_PERK | <868..1067 | CDD:270950 | 83/232 (36%) | ||
| S_TKc | <873..1065 | CDD:214567 | 81/225 (36%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D433474at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.920 | |||||