Protein Alignment Gcn2 and pkr3

DIOPT Version :9

• Sequence 1: NP_001263142.1
• Gene: Gcn2 / 43709
• FlyBaseID: FBgn0019990
• Length: 1591
• Species: Drosophila melanogaster
• Sequence 2: XP_031758368.1
• Gene: pkr3 / 100141483
• XenbaseID: XB-GENE-12565119
• Length: 534
• Species: Xenopus tropicalis
• Alignment Length: 443
• Identity: 121/443 - (27%)
• Similarity: 182/443 - (41%)
• Gaps: 139/443 - (31%)

  Fly   457 VDKCNSDRTLSASELLEHPFLRFYVDNGQQQVMPLPQQQHPNTVQRTGSAMPYQIPTLALSQSRL 521
            |.:.|.:|::....|          .||..||:....::.|:..|.|.:.:          ||.|
 Frog   211 VSESNGNRSIERRSL----------GNGATQVISAVTERSPHRTQSTANFV----------QSPL 255

  Fly   522 RTEFEVLMYLGKGAFGDVLKVRNILDNREYAIKRIPLPARSRQLYKKMTREVELLSRLNHENVVR 586
             .|||.:..|..|.||.|.|....:|.:.||:|::      :...:|...||:.|:.|:|.|:||
 Frog   256 -WEFEDITKLSTGGFGKVFKALKTMDKKYYAVKKV------KMRNEKCKLEVQALASLDHPNIVR 313

  Fly   587 YFNSWIESVDDADAAEMDKLLGGEWSQSQQDLSVKPAKSPQLGPTLEEDEDEEDSSSSMWNGYIP 651
            ||:||         ..||..|...:|.|
 Frog   314 YFHSW---------TGMDYSLDTSYSCS------------------------------------- 332

  Fly   652 NMEDSDSDGIEFVDSNGKVAVYDDEEQEDSTRGKTNSPKPLMQVMYIQMEFCEKCTLRTAIDDNL 716
              ..|::||:.                               :.::|||||||...|:..|....
 Frog   333 --TSSNTDGMN-------------------------------EYLFIQMEFCENGDLKNWIRKMK 364

  Fly   717 FNDTDRLWRLFREIAEGLAHIHQQGIIHRDLKPVNIFLDSHDQIKIGDFGLATTSFLALQAHDAA 781
            ..|..:...:||:|.||:.:||.:.:|||||||.|||.....::||||.||.|
 Frog   365 IVDKVKSLNIFRQIVEGVLYIHSEKLIHRDLKPANIFFAKDMRVKIGDLGLVT------------ 417

  Fly   782 PAPVNQITSAEDGTG---TGKVGTTLYVAPELTGNASKSVYNQKVDMYTLGIILFE-MCQPPFDT 842
                 |:.|.|....   |..:||..|:|||    ..:::||.:||::.||:||.| :|  .|.|
 Frog   418 -----QMASEESTEALLRTHDIGTPSYMAPE----QHENIYNCEVDIFALGLILVELLC--IFGT 471

  Fly   843 SMERAQTIMALRNVSINIPDAMLKDPKYE-KTVKMLQWLLNHDPAQRPTAEEL 894
            ..||......:||  ..:|:..:....|| .|:|:   :|:.||.:||||.:|
 Frog   472 EHERYVEWKKIRN--CQLPETFVAKYPYEICTIKL---MLSRDPKKRPTATKL 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gcn2	NP_001263142.1	RWD	17..130	CDD:214735
		PK_eIF2AK_GCN2_rpt1	261..476	CDD:270914	4/18 (22%)
		STKc_EIF2AK4_GCN2_rpt2	518..898	CDD:270948	110/382 (29%)
		S_TKc	525..895	CDD:214567	106/375 (28%)
		HisS	974..1414	CDD:223202
		class_II_aaRS-like_core	974..>1137	CDD:294192
pkr3	XP_031758368.1	DSRM_RNAse_III_family	3..69	CDD:380682
		DSRM_SF	117..183	CDD:412133
		PKc_like	257..523	CDD:419665	107/376 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433474at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010