Protein Alignment Gcn2 and pkr2

DIOPT Version :9

• Sequence 1: NP_001263142.1
• Gene: Gcn2 / 43709
• FlyBaseID: FBgn0019990
• Length: 1591
• Species: Drosophila melanogaster
• Sequence 2: XP_031758367.1
• Gene: pkr2 / 100141482
• XenbaseID: XB-GENE-1011407
• Length: 431
• Species: Xenopus tropicalis
• Alignment Length: 493
• Identity: 147/493 - (29%)
• Similarity: 204/493 - (41%)
• Gaps: 135/493 - (27%)

  Fly   425 GAGQSSSCGDLPA----LGALVESLMPT-----NSYEMRDFVDKCNSDRTLSASELLEHPFLRFY 480
            |.|:|....|..|    |.||.....|:     ::.:..|.|....|:.|.::|:.|
 Frog    40 GQGRSRKAADKEAARTGLAALQNRGKPSQARQPSAADSWDPVPSSGSNSTSNSSQSL-------- 96

  Fly   481 VDNGQQQVMPLPQQQHPNTVQRTGSAMPYQIPTLALSQSRLRTEFEVLMYLGKGAFGDVLKVRNI 545
               |........::...:|.|.|       :||..:.||.|| |||.:..|..|.||.|.|....
 Frog    97 ---GSDATEGSSERSSSHTTQST-------VPTTNVEQSPLR-EFENVTELSSGGFGIVYKAWKP 150

  Fly   546 LDNREYAIKRIPLPARSRQLY-KKMTREVELLSRLNHENVVRYFNSWIESVDDADAAEMDKLLGG 609
            :|...||:|::       ::| :|...||:.|:||:|.|:|||||||         ..||..|
 Frog   151 MDLNYYAVKKV-------KMYNEKCKSEVQALARLDHPNIVRYFNSW---------TGMDYFL-- 197

  Fly   610 EWSQSQQDLSVKPAKSPQLGPTLEEDEDEEDSSSSMWNGYIPNM------EDSDSDGIEFVDSNG 668
                                     |.....||||..|....|:      ||..||
 Frog   198 -------------------------DTSSLSSSSSSNNNQSTNVSLFRTREDCSSD--------- 228

  Fly   669 KVAVYDDEEQEDSTRGKTNSPKPLMQVMYIQMEFCEKCTLRTAIDDNLFNDTDRLWRLFREIAEG 733
                         ||..::......:.:||||||||...||..|.:....|......:|.:|.:|
 Frog   229 -------------TRNSSSDTDGRNEYLYIQMEFCENGDLRNWIREMKEVDKKNSLDIFWQIVKG 280

  Fly   734 LAHIHQQGIIHRDLKPVNIFLDSHDQIKIGDFGLATTSF------LALQAHDAAPAPVNQITSAE 792
            :|:||.|.:|||||||.|||.....::|||||||.|..|      ..|:.|
 Frog   281 VAYIHSQKLIHRDLKPENIFFSKDKKVKIGDFGLVTQIFSEGSTKALLRTH-------------- 331

  Fly   793 DGTGTGKVGTTLYVAPELTGNASKSVYNQKVDMYTLGIILFE-MCQPPFDTSMERAQTIMALRNV 856
             ||||..     |:|||  ....|:.||.:||::.||:||.| :|  .|.|..||...:|.:||
 Frog   332 -GTGTYP-----YMAPE--QQHKKTNYNSEVDIFALGLILVELLC--IFGTEHERRDELMKIRN- 385

  Fly   857 SINIPDAMLKDPKYEKTVKMLQWLLNHDPAQRPTAEEL 894
             ...|.|.:  .||...:..::.:|:.||..||.|.:|
 Frog   386 -CQFPKAFV--AKYPCEISTIRLMLSRDPKNRPAAIKL 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gcn2	NP_001263142.1	RWD	17..130	CDD:214735
		PK_eIF2AK_GCN2_rpt1	261..476	CDD:270914	15/59 (25%)
		STKc_EIF2AK4_GCN2_rpt2	518..898	CDD:270948	126/391 (32%)
		S_TKc	525..895	CDD:214567	121/384 (32%)
		HisS	974..1414	CDD:223202
		class_II_aaRS-like_core	974..>1137	CDD:294192
pkr2	XP_031758367.1	DSRM_RNAse_III_family	2..62	CDD:380682	8/21 (38%)
		PKc_like	129..424	CDD:419665	122/385 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433474at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920