Protein Alignment Ugt35D1 and Ugt2a1

DIOPT Version :10

• Sequence 1: NP_651866.1
• Gene: Ugt35D1 / 43708
• FlyBaseID: FBgn0051002
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_444414.2
• Gene: Ugt2a1 / 94215
• MGIID: 2149905
• Length: 528
• Species: Mus musculus
• Alignment Length: 554
• Identity: 154/554 - (27%)
• Similarity: 271/554 - (48%)
• Gaps: 72/554 - (12%)

  Fly     6 LLVCLLP----GYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEIT-------------SVS 53
            :|:|.|.    |.|.|..:| ::|: ..||:......:..|....|.:|             |:|
Mouse     5 ILLCSLQISLLGMSLGGNVL-IWPM-EGSHWLNVKIIIDELLRKEHNVTVLVASGALFITPSSIS 67

  Fly    54 PYPQREPFRNIHDIPVPEVFENFNEV--------LRIASTPRSTW----QSSDFINEYVL---NL 103
            |....|.:      |||...|....|        |....:|.:.|    :.:..|.|:.|   .:
Mouse    68 PSLTFEIY------PVPFGKEKIESVIKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSRGI 126

  Fly   104 TKTVLNNEGVRRDILGPQKPHFDLVIMD--LWRMDVLSGLAAYFDAPIIGMASYGTDWKIDELMG 166
            ...||.||.:...:   ||..|::::.|  ....|:   :|.....|.|....:.....:::..|
Mouse   127 CDGVLKNEKLMSKL---QKEKFEVLLSDPVFPCGDI---VALKLGIPFIYSLRFSPASTVEKHCG 185

  Fly   167 NVS-PISYLQSPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQF--FPSVAERKP 228
            .|. |.||:.:..|...|..::.:|:.:.:  ::...:|.:      |||:.|:  :.:.|..:|
Mouse   186 KVPFPPSYVPAILSELTDQMSFTDRVRNFI--SYRMQDYMF------ETLWKQWDSYYTKALGRP 242

  Fly   229 --LSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGVIYF 291
              |.|.....::.|:..::....||||:||...|||||. ...:.|..|::.|:|.:||.|::.|
Mouse   243 TTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHC-KPAKPLPKEMEEFVQTSGEHGIVVF 306

  Fly   292 SLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKPPNVFISKWFPQQAILAHPNVKL 356
            |||:.|  |:|::::..::....|.:||:::|:::.::......|..:..|.||..:|.||..:.
Mouse   307 SLGSMV--KNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRA 369

  Fly   357 FITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTN 421
            ||||||.....|:|:||.||:|:|...||..|:.|::..|..:.:|:..|||.:..:.:..::..
Mouse   370 FITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINE 434

  Fly   422 KSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFLVG 486
            .|::|.|...:..:.|||:||::.|::|.|:|:.||||.|::||..||.:.:||||||.|
Mouse   435 PSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIG----- 494

  Fly   487 ALVILGIVTYLLVMTLRKCLFLIKR-GKCEAIKK 519
              .:|..|...:::..:.|||:.:: ||....||
Mouse   495 --FLLACVASAILLVAKCCLFIFQKVGKTGKKKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	GT1_Gtf-like	18..449	CDD:340817	120/465 (26%)
Ugt2a1	NP_444414.2	UDPGT	21..516	CDD:278624	144/526 (27%)