DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35D1 and UGT74F1

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_181912.1	Gene:	UGT74F1 / 818988	AraportID:	AT2G43840	Length:	449	Species:	Arabidopsis thaliana

Alignment Length:	495	Identity:	111/495 - (22%)
Similarity:	187/495 - (37%)	Gaps:	120/495 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ILAVFPLPSSSHYFFALPYLKSLASLG----HEITSVSPYPQREPFRNIH-----DIPVPEVFEN 75
            :||| |.||..|......:.|.|.|.|    |.:|:..       |..||     .|.:..:.:.
plant     8 VLAV-PFPSQGHITPIRQFCKRLHSKGFKTTHTLTTFI-------FNTIHLDPSSPISIATISDG 64

  Fly    76 FNEVLRIASTPRSTWQSSDFINEYVLNL----TKTVLNNEGVRRDILGPQKPHFDLVIMDL---W 133
            :::         ..:.|:..:.||:.|.    :|||.:   :.|.......| ...::.|.   |
plant    65 YDQ---------GGFSSAGSVPEYLQNFKTFGSKTVAD---IIRKHQSTDNP-ITCIVYDSFMPW 116

  Fly   134 RMDVLS--GLAAYFDAPIIGMASYGTDWKIDELMGNVSPISYLQSPSSRFYDLEAYGERLLHLME 196
            .:|:..  ||||   ||....:.            .|:.|:||...::....|......||.|.:
plant   117 ALDLAMDFGLAA---APFFTQSC------------AVNYINYLSYINNGSLTLPIKDLPLLELQD 166

  Fly   197 RTFSYMNYKWRHVRKQETLYSQFFPSVAERKPLSEISRNF---DLVLVNQH-------------- 244
            .. :::.....|:...|.:..||              .||   |.||||..
plant   167 LP-TFVTPTGSHLAYFEMVLQQF--------------TNFDKADFVLVNSFHDLDLHEEELLSKV 216

  Fly   245 ---FTLGP--PRPYVPNMIQVGG---LHVDHSTEALSAELDHFIQGAGESGVIYFSLGTNVKSKS 301
               .|:||  |..|:...|:...   |::....||  |....::....|..|:|.:.|:..|..|
plant   217 CPVLTIGPTVPSMYLDQQIKSDNDYDLNLFDLKEA--ALCTDWLDKRPEGSVVYIAFGSMAKLSS 279

  Fly   302 LSEDRRKVLLETFASLPQRIVW----KFEDELLPGKPPNV-----FISKWFPQQAILAHPNVKLF 357
            ...:.....:..|:.|     |    ..|.:|.||....|     .:.||.||..:|::..:..|
plant   280 EQMEEIASAISNFSYL-----WVVRASEESKLPPGFLETVDKDKSLVLKWSPQLQVLSNKAIGCF 339

  Fly   358 ITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQV-GLGLVLNIKQMTS----EEFRSTIIR 417
            :||.|..||:|.:..|.||:.:|...||..|..:::.| .:|:.:..::.:.    ||...:|..
plant   340 MTHCGWNSTMEGLSLGVPMVAMPQWTDQPMNAKYIQDVWKVGVRVKAEKESGICKREEIEFSIKE 404

  Fly   418 LLTNKSFEETARITAARYRDQPMKPM----ETAIWWTEYV 453
            ::..:..:| .:..|.::||..:|.:    .|.|...|:|
plant   405 VMEGEKSKE-MKENAGKWRDLAVKSLSEGGSTDININEFV 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	111/495 (22%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	105/485 (22%)
UGT74F1	NP_181912.1	PLN02173	1..449	CDD:177830	111/495 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050