Protein Alignment Ugt35D1 and ugt1b4

DIOPT Version :10

• Sequence 1: NP_651866.1
• Gene: Ugt35D1 / 43708
• FlyBaseID: FBgn0051002
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001166239.2
• Gene: ugt1b4 / 795050
• ZFINID: ZDB-GENE-080227-13
• Length: 533
• Species: Danio rerio
• Alignment Length: 582
• Identity: 153/582 - (26%)
• Similarity: 260/582 - (44%)
• Gaps: 129/582 - (22%)

  Fly     6 LLVCLLPGYSEGARI-------------LAVFPLPSSSHYFFALPYLKSLASLGHEITSVSP--- 54
            :::||:.|....|.:             |.|.|: ..||:.......:.:...||.:..|.|
Zfish     9 VIICLVVGVVCSAVVDQKLSRNSSWTGKLLVVPM-DGSHWTGVKAVAEEMGRRGHTVIVVIPEIS 72

  Fly    55 ---------YPQREPFRNIHDIPVPEVFENFNEVL----------------------RIASTPRS 88
                     ..::.|.:...|:....:.|:.|||.                      ...||..|
Zfish    73 MRLGPGKHYITKKFPVQYKQDLINQIMVEHVNEVAASEQSLLKTVTSIMYRFGKIIDHFISTSES 137

  Fly    89 TWQSSDFINEYVLNLTKTVLNNEGVRRDILGPQKPHFDLVIMDLWRMDVLSGLAAYFDAPIIGMA 153
            .:|..:.| |::              ||      .:||.|:.:. .|.:.:.||.....|.:.|
Zfish   138 LFQEQELI-EFL--------------RD------QNFDAVLTNP-AMPMGAILAYNLSVPAVYM- 179

  Fly   154 SYGTDWKIDELMGNV---------SPISYLQSPSSRFYDLEAYGERLLH------------LMER 197
                      |.|.:         :|.||:....::..|...:.||:::            ||..
Zfish   180 ----------LRGIMCESKATACPNPPSYIPRFFTQISDRMTFSERVINTLVSLLEPLMCRLMLG 234

  Fly   198 TFSYMNYKWRHVRKQETLYSQFFPSVAERKPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGG 262
            :|..|..|:.|                ....::||.....:.|:...|||..|:|.:||||.:||
Zfish   235 SFEEMTSKFLH----------------RDVSITEILSTAAVWLMRYDFTLEFPKPLMPNMITIGG 283

  Fly   263 LHVDHSTEALSAELDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFED 327
            ::.: ....|:.|::.|:.|:||.|::.||||:.|  .|:.:::..:..:.|:.:|||::|::..
Zfish   284 INCE-VKNPLTKEVEEFVNGSGEHGIVVFSLGSLV--SSMPKEKADIFFKAFSMIPQRVLWRYTG 345

  Fly   328 ELLPGKPPNVFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHV 392
            |:....|.||.:.||.||..:|.||..:.||||||.....|.|.||.||:.||...||..|:..|
Zfish   346 EIPNNVPENVKLMKWLPQNDLLGHPKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQADNVHRV 410

  Fly   393 RQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHK 457
            ...|:|::|:|..:|.|.....:..::.|.|:::..:..:|.:.|:|::|::.|::|||:|:.||
Zfish   411 ATRGVGVILSIHDITVETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVMRHK 475

  Fly   458 GAAHMQVAGKDLGFVRYHSLDVFGTFLVGALVILGIVTYLLVMTLRKCLFLIKRGKCEAIKK 519
            ||.|::.|..:|.:::||||||.|..|   |::| |||    :.:.||..|..|..|...:|
Zfish   476 GADHLRPAAHELNWLQYHSLDVIGFML---LIVL-IVT----LAMLKCCSLCWRRCCRKTQK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	GT1_Gtf-like	18..449	CDD:340817	120/498 (24%)
ugt1b4	NP_001166239.2	UDPGT	35..529	CDD:278624	148/554 (27%)