Protein Alignment Ugt35D1 and ugt2a4

DIOPT Version :10

• Sequence 1: NP_651866.1
• Gene: Ugt35D1 / 43708
• FlyBaseID: FBgn0051002
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001170804.2
• Gene: ugt2a4 / 791613
• ZFINID: ZDB-GENE-080721-23
• Length: 533
• Species: Danio rerio
• Alignment Length: 540
• Identity: 150/540 - (27%)
• Similarity: 259/540 - (47%)
• Gaps: 63/540 - (11%)

  Fly     6 LLVCLL-----PGYSEGARILAVFPLPSS-SHYFFALPYLKSLASLGHEIT-------SVSPYPQ 57
            ||||||     .|:|  .|:|.   :|.. ||:......:::|....|.:|       ...|:.|
Zfish     6 LLVCLLLCGVDVGWS--GRVLV---MPGEYSHWHNMRAIIEALVDRNHSVTVLVSSSSPTVPHTQ 65

  Fly    58 REPFR------NIHDIPVPEVFENFNEVLRIASTPRS------TWQSSDFINEYVLNLTKTVLNN 110
            :..|.      |:.......::.:|.. |.:..|...      .|:..........::.:::|.|
Zfish    66 KARFDYHVFKVNMDKEEAKVIWSDFTH-LWMKETDSKLERGFLIWRVMSNFRRLAADVCRSLLQN 129

  Fly   111 EGVRRDILGPQKPHFDLVIMDLWRMDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNV-SPISYL 174
            :.:.: :||  :.|:|::..|. .|.....:|...:.|.:........:..:.:.|.: :|.||:
Zfish   130 DDLLQ-MLG--ESHYDVLFSDP-MMPCSDLMAQTLNIPQVISLRLTFAYTFERMCGQMPAPPSYV 190

  Fly   175 QSP------SSRFYDLEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQFFPSVAERKP--LSE 231
            .:.      :.|...:|.....||:.:..|...:|    .:...:.||::.     ..||  :.|
Zfish   191 PAVALTDHLTDRMSFMERVENMLLYFIHTTVFRLN----TMLTVDRLYTEI-----RGKPTTMCE 246

  Fly   232 ISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGVIYFSLGTN 296
            .....|:.|:..::....|||:.||...|||||. ...:.||.|::.|:|.:|:.||:.||||:.
Zfish   247 TMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHC-KPAKPLSKEMEEFVQSSGDHGVVVFSLGSM 310

  Fly   297 VKSKSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKPPNVFISKWFPQQAILAHPNVKLFITHG 361
            :  |:|:.:|...:......:||::||::..:......||..|..|.||..:|.||..|.|||||
Zfish   311 I--KNLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHG 373

  Fly   362 GLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEE 426
            |.....|:|:||.||:|||...||..|:.|::..|..:||:|..:.|::....:..:|.|.|::|
Zfish   374 GTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSYKE 438

  Fly   427 TARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFLVGALVIL 491
            :....:..:.||||||::.|::|.|:|:.:|||.|::|...:|.:.:||.||| ..||   |.|.
Zfish   439 SIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDV-AAFL---LSIA 499

  Fly   492 GIVTYLLVMTLRKCLFLIKR 511
            .::|:|.|   :.|.||.:|
Zfish   500 ALITFLWV---KACCFLFRR 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	GT1_Gtf-like	18..449	CDD:340817	117/459 (25%)
ugt2a4	NP_001170804.2	UDPGT	21..520	CDD:278624	142/523 (27%)