Protein Alignment Ugt35D1 and UGT2B15

DIOPT Version :9

• Sequence 1: NP_651866.1
• Gene: Ugt35D1 / 43708
• FlyBaseID: FBgn0051002
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001067.2
• Gene: UGT2B15 / 7366
• HGNCID: 12546
• Length: 530
• Species: Homo sapiens
• Alignment Length: 559
• Identity: 156/559 - (27%)
• Similarity: 270/559 - (48%)
• Gaps: 90/559 - (16%)

  Fly     4 IFLLVCLLPGYSEGA--RILAVFPLPSSSHYFFALPYLKSLASLGHEIT---------------- 50
            :|||:.|...:|.|:  ::| |:| ...||:......|:.|...|||:|
Human     8 VFLLIQLSCYFSSGSCGKVL-VWP-TEYSHWINMKTILEELVQRGHEVTVLTSSASTLVNASKSS 70

  Fly    51 --SVSPYPQ-------REPFRNIHDIPVPEVFEN-----FNEVLRIASTPRSTWQSSDFINEYVL 101
              .:..||.       .:....|.|..:..|.:|     |:::..:.      |:..|:.|:
Human    71 AIKLEVYPTSLTKNYLEDSLLKILDRWIYGVSKNTFWSYFSQLQELC------WEYYDYSNK--- 126

  Fly   102 NLTKTVLNNEGVRRDILGPQKPHFDLVIMDLWRMDVLSG----LAAYFDAPIIGMASYGTDWKID 162
             |.|..:.|:.:...:   |:..||:::     .|.|:.    ||..|:.|.:....:...:..:
Human   127 -LCKDAVLNKKLMMKL---QESKFDVIL-----ADALNPCGELLAELFNIPFLYSLRFSVGYTFE 182

  Fly   163 ELMGN-VSPISYLQSPSSRFYDLEAYGER---LLHLMERTFSYMNY---KWRHVRKQETLYSQFF 220
            :..|. :.|.||:....|...|...:.||   ::|::...|.:..|   ||          .||:
Human   183 KNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIHMLYFDFWFQIYDLKKW----------DQFY 237

  Fly   221 PSVAER-KPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAG 284
            ..|..| ..|.|.....::.|:..::....|||::||:..|||||. ...:.|..|::.|:|.:|
Human   238 SEVLGRPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLHC-KPAKPLPKEMEEFVQSSG 301

  Fly   285 ESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKPPNVF-----ISKWFP 344
            |:|::.||||:.:  .::||:...::....|.:||:::|:|:     ||.||..     :.||.|
Human   302 ENGIVVFSLGSMI--SNMSEESANMIASALAQIPQKVLWRFD-----GKKPNTLGSNTRLYKWLP 359

  Fly   345 QQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSE 409
            |..:|.||..|.||||||.....|:|:||.||:|:|...||..|:.|::..|..|.::|:.|:|.
Human   360 QNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSR 424

  Fly   410 EFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRY 474
            :..:.:..::.:..::|.....:..:.||||||::.|::|.|:|:.||||.|::||..:|.:::|
Human   425 DLLNALKSVINDPVYKENVMKLSRIHHDQPMKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQY 489

  Fly   475 HSLDVFGTFLVGALVILGIVTYLLVMTLRKCLFLIKRGK 513
            |||||....|.....::.|:|...:...||   |.|:||
Human   490 HSLDVIAFLLACVATVIFIITKFCLFCFRK---LAKKGK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	137/506 (27%)
		UDPGT	30..511	CDD:278624	144/527 (27%)
UGT2B15	NP_001067.2	egt	8..508	CDD:223071	148/537 (28%)
		UDPGT	24..518	CDD:278624	144/531 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150279
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8458
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.690