Protein Alignment Ugt35D1 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_651866.1
• Gene: Ugt35D1 / 43708
• FlyBaseID: FBgn0051002
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001034638.1
• Gene: Ugt1a5 / 574523
• RGDID: 1583689
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 539
• Identity: 144/539 - (26%)
• Similarity: 252/539 - (46%)
• Gaps: 73/539 - (13%)

  Fly     4 IFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSP----YPQREPFRNI 64
            :.||:..|| ::||.::| |||: ..||:......::.|.:.||:...::|    :.:.|.|..:
  Rat    13 LLLLLYALP-WAEGGKVL-VFPM-EGSHWLSMRDVVRELHARGHQAVVLAPEVTVHIKEEDFFTL 74

  Fly    65 HDIPVP--------EVFENFNEVLRIASTPRSTWQSSDF---INEYVLNLTKTVLNNEGVRRDIL 118
            ...|||        ::..|...|....:..::..::|:.   |:..:|.....:|:|..:.:.:
  Rat    75 QTYPVPYTRQGFRQQMMRNIKVVFETGNYVKTFLETSEILKNISTVLLRSCMNLLHNGSLLQHL- 138

  Fly   119 GPQKPHFDLVIMDLWRMDVL---SGLAAYFDAPIIGMASY---GTDWKIDELMGNVSPISYLQSP 177
              ....||:|:.|    .|:   :.||.|...|.:....|   |.|   .|......|.||:.:.
  Rat   139 --NSSSFDMVLTD----PVIPCGAVLAKYLGIPTVFFLRYIPCGID---SEATQCPKPSSYIPNL 194

  Fly   178 SSRFYDLEAYGERLLHLMERT-------FSYMNYKWRHVRKQETLYSQFFPSVAERKPLSEISRN 235
            .:...|...:.:|:.:::...       ||:..|        |:|.|:.            :.|.
  Rat   195 LTMLSDHMTFLQRVKNMLYPLALKYICHFSFTRY--------ESLASEL------------LQRE 239

  Fly   236 FDLVLVNQH---------FTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGVIYF 291
            ..||.|..|         |....|||.:|||:.:||::. ...:.||.|.:.::..:||.|::.|
  Rat   240 VSLVEVLSHASVWLFRGDFVFDYPRPVMPNMVFIGGINC-VIKKPLSQEFEAYVNASGEHGIVVF 303

  Fly   292 SLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKPPNVFISKWFPQQAILAHPNVKL 356
            |||:.|  ..:.|.:...:.|....:||.::|::..........|..:.||.||..:|.||..:.
  Rat   304 SLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARA 366

  Fly   357 FITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTN 421
            ||||.|.....|.|.:|.||:.:|...||..|...:...|.|:.||:.:||:::..:.:..::.|
  Rat   367 FITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINN 431

  Fly   422 KSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFLVG 486
            ||::|.....::.::|:|::|::.|::|.|||:.||||.|::.|..||.:.:||||||.|..|..
  Rat   432 KSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAI 496

  Fly   487 ALVILGIVTYLLVMTLRKC 505
            .|.::.||........|||
  Rat   497 VLTVVFIVYKSCAYGCRKC 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	GT1_Gtf-like	18..449	CDD:340817	112/467 (24%)
Ugt1a5	NP_001034638.1	UDPGT	26..522	CDD:278624	138/525 (26%)