Protein Alignment Ugt35D1 and ugt1b1

DIOPT Version :10

• Sequence 1: NP_651866.1
• Gene: Ugt35D1 / 43708
• FlyBaseID: FBgn0051002
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001170917.1
• Gene: ugt1b1 / 558508
• ZFINID: ZDB-GENE-080227-10
• Length: 528
• Species: Danio rerio
• Alignment Length: 543
• Identity: 166/543 - (30%)
• Similarity: 267/543 - (49%)
• Gaps: 62/543 - (11%)

  Fly     6 LLVCLLPGYS--EGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSP-----YPQREPFRN 63
            ||:.|..|..  :|.|:| |.|: ..||:.........||..||::..:.|     ....|.||.
Zfish    15 LLLWLSAGLRPVQGGRVL-VMPV-EGSHWLSMKVLATELARRGHDVLVLVPEKNILIQSSELFRT 77

  Fly    64 IHDIPVPEVFENFNEVLR---IASTPRSTWQSSDFIN-EYVLNLT-------KTVLNNEGVRRDI 117
             ...||....|..::.|:   .....||......|:. |.:||.|       :::|.||.:.|.:
Zfish    78 -ETFPVKISKEQLSKSLKGFQQGVFTRSPALMDVFVQLERLLNFTGSQVEGCESLLYNEPLMRKL 141

  Fly   118 LGPQKPHFDLVIMDLWR------MDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNV-SPISYLQ 175
               ::.:|:|::.|.:.      ...|...|.||   :.||..     .||.|.... ||.||:.
Zfish   142 ---KEQNFELMLTDPFLPCGPIIATALGVPAVYF---LRGMPC-----GIDLLASQCPSPPSYVP 195

  Fly   176 SPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQFFPSVAE--RKPLS--EISRNF 236
            ...|...|...:.||:.:.....|..:..|        .:|:.|....|.  :|.::  ||....
Zfish   196 RFHSGTSDKMNFVERIRNFFMSGFELVLCK--------VMYASFDELAARYLKKDVTYKEIIGRG 252

  Fly   237 DLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGVIYFSLGTNVKSKS 301
            .|.|....||...|||.:|||:.:||::...|.| :|||::.|:.|:||.|::.||||:.|  .|
Zfish   253 ALWLHRYDFTFEYPRPIMPNMVFIGGINCQKSAE-ISAEVEEFVNGSGEHGIVVFSLGSLV--SS 314

  Fly   302 LSEDRRKVLLETFASLPQRIVWKFEDELLPGKPPNVFISKWFPQQAILAHPNVKLFITHGGLLST 366
            :.:::..:..:.|:.:|||::|::..|:....|.||.:.||.||..:|.||..:.||||||....
Zfish   315 MPKEKADIFFKAFSMIPQRVLWRYTGEIPDNVPENVKLMKWLPQNDLLGHPKARAFITHGGTHGI 379

  Fly   367 IESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEETARIT 431
            .|.|..|.||:.||...||..|:..|...|:|::|:|..:|.|.....:..::.|.|:::..:..
Zfish   380 YEGICRGVPMVMLPLFGDQADNVHRVATRGVGVILSIHDITVETLLDALNSVINNSSYKQKMQKL 444

  Fly   432 AARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFLVGALVILGIVTY 496
            :|.:.|:|::|::.|::|||:|:.||||.|::.|..:|.:::||||||.|..|   |::| |||
Zfish   445 SAIHNDRPIQPLDLAVFWTEFVMRHKGADHLRPAAHELNWLQYHSLDVIGFML---LIVL-IVT- 504

  Fly   497 LLVMTLRKCLFLIKRGKCEAIKK 519
               :.:.||..|..|..|...:|
Zfish   505 ---LAMLKCCSLCWRRCCRKTQK 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	GT1_Gtf-like	18..449	CDD:340817	131/457 (29%)
ugt1b1	NP_001170917.1	UDPGT	29..524	CDD:278624	160/527 (30%)