DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35D1 and ugt5g2

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001186305.1	Gene:	ugt5g2 / 556049	ZFINID:	ZDB-GENE-081028-66	Length:	534	Species:	Danio rerio

Alignment Length:	555	Identity:	148/555 - (26%)
Similarity:	262/555 - (47%)	Gaps:	102/555 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSV-----------SPY---- 55
            ||:.|..||:  |..:.|||: ..||:......:|.|.|.|||::.:           |||
Zfish    14 LLLSLPSGYN--ADKILVFPI-DGSHWVNMEVLVKKLQSRGHELSVIRLEDSWFIKGNSPYYSSI 75

  Fly    56 --PQREPFRNIHDIPVPEVFENFNEVLRIASTPRS------TWQSSDFINEYVLN--------LT 104
              ..::.|.::      ::||  ..|.:|....|.      ..|.|:||.  :|.        :.
Zfish    76 TVTLKKKFIDL------DLFE--TAVKKILDARRDGPIMGVLAQMSEFIG--ILKVGHGANIAML 130

  Fly   105 KTVLNNEGVRRDILGPQKPHFDLVIMDLWRMDVLSG---LAAYFDAPIIGMASYGTDW-KIDELM 165
            .::|.|:.:...|   :..::||::.|    ..:.|   ||.|...|::    |...| ...|..
Zfish   131 TSMLENKVLMSQI---KMANYDLMLTD----PAMPGGVILAHYLHLPMV----YNVRWMSFGEGH 184

  Fly   166 GNV--SPISYLQSPSSRFYDLEAYGERLLHLMERTFSYMNY-------KWRHVRKQETLYSQFFP 221
            .::  ||||::..|.|...|       .:.|:||:.::::|       :|..:....:|....||
Zfish   185 FSIAPSPISFVPVPGSGLTD-------RMGLLERSRNFLHYGLNLIQERWMVIPMYTSLLLNHFP 242

  Fly   222 SVAERKPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGES 286
            ...:   |..:.|:.:|.||...|....|||.:||::.:||... ...:.|.|:|:.|:|.:|:.
Zfish   243 PGTD---LLTMQRSAELWLVRADFVFEFPRPSMPNLVYIGGFQC-RPAKPLPADLEEFMQSSGDH 303

  Fly   287 GVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKPP-----NVFISKWFPQQ 346
            ||:..||||.:  ..|.::..:.:...||.:||:::|:|     .|:.|     |..:.:|.||.
Zfish   304 GVVVMSLGTLI--AGLPKEVMEAIASAFAQIPQKVIWRF-----IGQRPSTLGNNTLLIQWLPQN 361

  Fly   347 AILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEF 411
            .:|.||..:.|:.|||.....|:|:||.|:||||.||||..|:..::..|...:|:....:::||
Zfish   362 DLLGHPKTRAFVAHGGTNGLYEAIYHGVPVLGLPLLFDQLDNIVRLQARGGARMLDAATCSTKEF 426

  Fly   412 RSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHS 476
            ...:..:|.|.::.:..:..:..:||:|:.|::.|::|.|:||.:|||.|::....::....|:.
Zfish   427 LVALTDILENPTYRQNMQKLSNLHRDRPLHPLDKAVYWIEFVLRNKGAPHLRAEAYNVSEFSYYC 491

  Fly   477 LDVFGTFLVGALVILGIVTYLLVMTLRKCLFLIKR 511
            |||           :.:|.::|:.||.....:.||
Zfish   492 LDV-----------VALVLFMLLGTLGGVYTICKR 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	137/504 (27%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	137/529 (26%)
ugt5g2	NP_001186305.1	egt	3..507	CDD:223071	145/545 (27%)
ugt5g2	NP_001186305.1	UDPGT	25..513	CDD:278624	140/538 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584624
Domainoid	1	1.000	252	1.000	Domainoid score	I2043
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.690