DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35D1 and Ugt35C1

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001097744.1	Gene:	Ugt35C1 / 53507	FlyBaseID:	FBgn0040256	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	523	Identity:	212/523 - (40%)
Similarity:	322/523 - (61%)	Gaps:	20/523 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IFLLVCLL---PGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRNIH 65
            |.::.|.|   |..||.|:|||..|.|..|.|.|...|||:||:.||::|.::.:..:|. .|:.
  Fly     7 IAIVFCALSAKPLESESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVINAFKNKET-PNMR 70

  Fly    66 DIPVPEVFENFNEVLRIASTPRSTWQSSDFINEYVLN-LTKTVLNNEGVRRDILGPQKPHFDLVI 129
            .|...:..|..:|::.:.:.| ..||..:.: :|:|| .....:.:|||:|.:...:.  ||||:
  Fly    71 FIEALKAHEFADEMMSLLNVP-LLWQQLNAM-DYILNKFIDVTMEDEGVQRLLNSGET--FDLVL 131

  Fly   130 MDLWRMDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNVSPISYLQSPSSRFYDLEAYGERLLHL 194
            .::..|:.:...|.:|:|.::|.:|:|||..|||..||:|||||....:|...|...:.|||.:.
  Fly   132 AEMLHMEPMYAFAQHFNATLVGFSSFGTDRTIDEAAGNISPISYNPLVTSPRTDRMTFLERLENH 196

  Fly   195 MERTFSYMNYKWRHVRKQETLYSQFFPSVAERKPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQ 259
            .|.....::..:.|:.....:|.::||:.  :|.|.|:..:|.|:|:.|||:|..||||:||||:
  Fly   197 YEVIVEDIHRHFVHLPHMRNVYKKYFPNA--KKTLEEVMDSFSLILLGQHFSLSYPRPYLPNMIE 259

  Fly   260 VGGLHVDHSTEALSAELDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQRIVWK 324
            |||:|:.|..:.|..::..||:|: ..||||||:|:|||||.|.::.|..||:|||.|.||::||
  Fly   260 VGGMHISHKPKPLPEDIKQFIEGS-PHGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQRVLWK 323

  Fly   325 FEDELLPGKPPNVFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNM 389
            |||:.:||||.||.|.||:||..|||||||||||:||||||:.||::.|||:|||||.:||..|:
  Fly   324 FEDDDMPGKPANVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNV 388

  Fly   390 DHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVL 454
            ...::||.||.|::..:..|:....|..|||:.|:.:.:...:.||||||...::.|:||||||:
  Fly   389 QRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVI 453

  Fly   455 SHKGAAHMQVAGKDLGFVRYHSLDVFGTFLVGALVILGIVTYLLVMTLRKCLFLIKRGKC---EA 516
            .|.||.|::...:||.|::.:|||.....|...|::.     ||::||...|...|:.||   :.
  Fly   454 RHNGAPHLRATSRDLNFIQLNSLDTLAVILAVPLLLA-----LLIVTLSCKLLGGKKQKCLHADK 513

  Fly   517 IKK 519
            :||
  Fly   514 LKK 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	193/461 (42%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	195/481 (41%)
Ugt35C1	NP_001097744.1	egt	1..470	CDD:223071	196/470 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	1	1.000	-	-		H55988
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	11	10.870