DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35D1 and Ugt35E1

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_652622.3	Gene:	Ugt35E1 / 53504	FlyBaseID:	FBgn0040253	Length:	527	Species:	Drosophila melanogaster

Alignment Length:	501	Identity:	302/501 - (60%)
Similarity:	395/501 - (78%)	Gaps:	2/501 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRNIHDIPV 69
            :|::.|.||:..||||||:||:||.|||:.||||||:|||||||||||||:|..||.:||:||.|
  Fly     8 YLIILLFPGFLYGARILALFPVPSHSHYYHALPYLKNLASLGHEITSVSPFPSEEPVKNIYDIYV 72

  Fly    70 PEVFENFNEVLRIASTPRSTWQSSDFINEYVLNLTKTVLNNEGVRRDILGPQKPHFDLVIMDLWR 134
            |||..:|:|:|:..:||::||:..|..||:|.|:||.|.||:||||:||.|.|..|||:|:|:|:
  Fly    73 PEVLNSFDELLKQMTTPKNTWEFFDATNEFVYNITKDVFNNDGVRREILRPGKAQFDLIIVDIWK 137

  Fly   135 MDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNVSPISYLQSPSSRFYDLEAYGERLLHLMERTF 199
            .|....|||||:|||||:|..|.||||||::||.||:||||||||..|:|:.:|.|:.|::|...
  Fly   138 YDAFYSLAAYFEAPIIGLAPCGIDWKIDEMVGNPSPMSYLQSPSSYLYNLDTFGGRVAHVVEVAI 202

  Fly   200 SYMNYKWRHVRKQETLYSQFFPSVAERKPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLH 264
            |:.|:.||:.:|.|.||.::||.:||.|||||||::..|||||||||||||||||||:|:|||:|
  Fly   203 SWFNWHWRYEQKHEALYKKYFPKIAETKPLSEISQDIALVLVNQHFTLGPPRPYVPNVIEVGGMH 267

  Fly   265 VDHSTEALSAELDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDEL 329
            :|...:||:.:|:.||||:||.|||||||||||::|::.:||:::|:|.|.|||||::||||||.
  Fly   268 IDEQPKALAQDLEDFIQGSGEHGVIYFSLGTNVRTKNMVDDRKRILIEAFGSLPQRVLWKFEDEE 332

  Fly   330 LPGKPPNVFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQ 394
            |...|.||.:.||.|||.:||||.|||||||||:.|||||||:||||||||..:|||.|:||:::
  Fly   333 LQDIPSNVLVRKWLPQQDLLAHPKVKLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKK 397

  Fly   395 VGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGA 459
            .|..|.||...|||:|.::||::|||.|.||.||||..||||||||||:|||:|||.|||.||||
  Fly   398 HGFCLSLNYHDMTSDELKATILQLLTEKRFEVTARIAGARYRDQPMKPLETAVWWTHYVLRHKGA 462

  Fly   460 AHMQVAGKDLGFVRYHSLDVFGTFLVGALVILGIVTYLLVMTLRKC 505
            .||:|||:.|.|..:|||||.||.|:  :::|.|:..||::....|
  Fly   463 PHMRVAGRKLSFFTHHSLDVLGTVLL--VILLVIIAILLIIVFSVC 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	282/456 (62%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	288/476 (61%)
Ugt35E1	NP_652622.3	egt	6..461	CDD:223071	279/452 (62%)
Ugt35E1	NP_652622.3	UDPGT	33..484	CDD:278624	280/450 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445569
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	1	1.000	-	-		H55988
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	12	11.800