DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35D1 and ugt2a1

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	XP_031759199.1	Gene:	ugt2a1 / 447975	XenbaseID:	XB-GENE-954008	Length:	735	Species:	Xenopus tropicalis

Alignment Length:	537	Identity:	135/537 - (25%)
Similarity:	248/537 - (46%)	Gaps:	89/537 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SSHYFFALPYLKSLASLGHEITSV------------------SPYP-----------QREPFR-- 62
            :||:......|:.||..|||:|::                  ..:|           ||:.|.
Frog   239 ASHWLNLRLILEELAHKGHEVTALVHSANMLIDHNLPSALKAEVFPVAFTKETFLTLQRDFFNFW 303

  Fly    63 --NIHDIPVPEVFENFNEVLRIASTPRSTWQSSDFINEYVLNLTKTVLNNEGVRRDILGPQKPHF 125
              .:|::...|::|:..  :.:||:.:....:.|           .||.|:.:...:   |...|
Frog   304 IYGVHNMSYWELYEHLK--VAVASSLKLQRDTCD-----------GVLKNKELMYKL---QNQKF 352

  Fly   126 DLVIMD-------LWRMDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNV-SPISYLQSPSSRFY 182
            |:|:.|       |        :|.....|.:....:.....::.|.|.: ||.||:....:.|.
Frog   353 DIVVADPVAPCGEL--------IAESLGVPFVYSFRFSMGNSLERLCGQLPSPFSYVPGAMTAFS 409

  Fly   183 DLEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQFFPSVAERKPLSEISRNFDLVLVNQHFTL 247
            |..::|:||.:.:...|..:.:.....:..:..||:.....|:   :.||....::.|:..::..
Frog   410 DKMSFGQRLANTVLYAFQDLIFSLVFQKNWDNYYSEILGRPAK---VCEIMGKAEIWLIRTYWDF 471

  Fly   248 GPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLE 312
            ..|||.:||...|||||. ...:.|..|::..::.:||.|::.||:|:.:  |:.|.:|..::..
Frog   472 EYPRPILPNFKFVGGLHC-APAKPLPEEIEKVVESSGEHGIVVFSMGSMI--KNFSNERTNIIAA 533

  Fly   313 TFASLPQRIVWKFEDELLPGKPP-----NVFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHH 372
            ..:.|||:::|::.     ||.|     |.....|.||..:|.||..|.||||||.....|:|:|
Frog   534 ALSQLPQKVLWRYS-----GKKPDALGENTITYDWIPQNDLLGHPKTKAFITHGGTNGIYEAIYH 593

  Fly   373 GKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEETARITAARYRD 437
            |.|::|:|...:|..|:.|::..|:.::|:..:|.:::....:..::.|.:::|.|...:..:.|
Frog   594 GVPIVGIPLFAEQPDNIVHMKSKGMAIMLDFNKMGTQDLLDAVNTVINNPTYKENAMRLSRIHHD 658

  Fly   438 QPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFLVGALVILGIVTYLLVMTL 502
            ||:||:::|::|.|:|:.||||.|::.|..:|.:.:||.|||.|...|...:...|....|....
Frog   659 QPVKPLDSAVFWIEFVMRHKGAKHLRPASHELTWYQYHCLDVIGFMFVCLFLFFYITITFLTFCY 723

  Fly   503 RKCLFLIKRGKCEAIKK 519
            :||        |...|:
Frog   724 KKC--------CRTTKE 732

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	119/478 (25%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	133/526 (25%)
ugt2a1	XP_031759199.1	UDPGT	238..733	CDD:278624	135/537 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H55988
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm9349
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.000