DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35D1 and Ugt303B2

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	492	Identity:	170/492 - (34%)
Similarity:	276/492 - (56%)	Gaps:	25/492 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 EGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSP--YPQREPFRNIHDIPVP---EVFEN 75
            :.|.||.|||....|.:....|.:|:|...||::|.|:|  ||.:  ...:..|.||   ::.:|
  Fly    24 QAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPADYPAK--IDGVRHIRVPMLNQLMQN 86

  Fly    76 FNEVLRIASTPRSTWQSSDFINEYVLNLTKTVLNNEGVRRDILGPQKPHFDLVIMDLWRMDVLSG 140
            ..:..:........|:....::....|::..:|||.||:. ::..:...||:::::...:|.|.|
  Fly    87 LMKNDQFFDALGDKWREGVLVSTIFYNVSHAILNNNGVQM-LMRDKSIRFDMIMVEASHLDALYG 150

  Fly   141 LAAYFDAPIIGMASYGTDWKIDELMGNVSPISYLQ-SPSSRFYD---LEAYGERLLHLMERTFSY 201
            ||.:::|.::|::.....|.||.|.||::|..|.. ||:....|   |..:...:....|:....
  Fly   151 LAEFYNATLLGISCMHMTWHIDYLAGNLAPSVYEPISPNGFALDNTFLSRWSNWIYITEEKLLER 215

  Fly   202 MNYKWRHVRKQETLYSQFFPSVAERKPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVD 266
            :.::...||    |:.:||...||:  |.|:...|.::|||.||::|..|..|||:|:|.|:|:.
  Fly   216 LVFRPAQVR----LFKKFFGYPAEK--LDELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLS 274

  Fly   267 HSTEALSAELDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDELLP 331
            ...|...|||..::..| |.|.||||:|.::..|.|.|:.:|.||..|..:.||::||.|..:|.
  Fly   275 EPPEPCGAELQKYLDEA-EHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWKSELSMLA 338

  Fly   332 GKPPNVFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVG 396
            .|..|:::....||:.:|||||::||||||||.|.:|:|.:|.||||||..||||.|:..|:..|
  Fly   339 NKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAG 403

  Fly   397 LGLVLNIKQMTSEEFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAH 461
            :..||:...:.::....||..||.|.|:.:.|:..||.:||:||.|::||||||||.|.::..:|
  Fly   404 MAKVLDPNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSH 468

  Fly   462 MQVAGKDLGFVRYHSLDVFGTF------LVGALVILG 492
            |::..:::..:||:.||...||      :.|:|:.||
  Fly   469 MRLNVEEIPLMRYYRLDSILTFGVRLGCVCGSLIFLG 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	158/454 (35%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	164/478 (34%)
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	158/449 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445599
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	11	10.800