Protein Alignment Ugt35D1 and Ugt1a3

DIOPT Version :10

• Sequence 1: NP_651866.1
• Gene: Ugt35D1 / 43708
• FlyBaseID: FBgn0051002
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_958827.1
• Gene: Ugt1a3 / 396551
• RGDID: 1549728
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 541
• Identity: 139/541 - (25%)
• Similarity: 255/541 - (47%)
• Gaps: 77/541 - (14%)

  Fly     4 IFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSP----YPQREPFRNI 64
            :.||:|.|| ::||.::| |||: ..||:......::.|.:.||:...::|    :.:.|.|..:
  Rat    13 LLLLLCALP-WAEGGKVL-VFPM-EGSHWLSMRDVVRELHARGHQAVVLAPEVTVHIKEEDFFTL 74

  Fly    65 HDIPVPEVFENFNEVL-------------------RIASTPRSTWQSSDFINEYVLNLTKTVLNN 110
            ...|||...|.:...|                   |:|:.        :.::.:.:...:.:|:|
  Rat    75 QTYPVPYTKEEYRHHLLGHLQNFFETEFSLKLVLQRMAAV--------NNVSTFYVRSCRGLLHN 131

  Fly   111 EGVRRDILGPQKPHFDLVIMDLWRMDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNVSPISYLQ 175
            ..:.:.:   ....||:|:.|.: ....:.||.|...|.:....              |.:..|:
  Rat   132 TALIQSL---NSSSFDVVLTDPF-FPCGAVLAMYLRVPAVFFLQ--------------SMLCELE 178

  Fly   176 SPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHVRKQETLY---------------SQFFPSVAE 225
            ..::...:..:|..|||.|.....|:::      |.:..||               ::....:.:
  Rat   179 FEATNSPNPSSYIPRLLTLNSDHMSFLD------RVKNMLYPVPWMYLCHVNYGSLARLASDLLQ 237

  Fly   226 RK-PLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGVI 289
            |: .:.||.|:..:.|:.:.|....|||::|||:.:||::. .:.:.||.|.:.::..:||.|::
  Rat   238 REVSVVEILRHASVWLLRKDFVFYYPRPFMPNMVFIGGINC-ANRKPLSQEFEAYVNASGEHGIV 301

  Fly   290 YFSLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKPPNVFISKWFPQQAILAHPNV 354
            .||||:.|  ..:.|.:...:.|....:||.::|::..........|..:.||.||..:|.||..
  Rat   302 VFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKA 364

  Fly   355 KLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLL 419
            :.||||.|.....|.|.:|.||:.:|...||..|...:...|.|:.||:.:||:::..:.:..::
  Rat   365 RAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVI 429

  Fly   420 TNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFL 484
            .|||::|.....::.::|:|::|::.|::|.|||:.||||.|::.|..||.:.:||||||.|..|
  Rat   430 NNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLL 494

  Fly   485 VGALVILGIVTYLLVMTLRKC 505
            ...|.::.||........|||
  Rat   495 AIVLTVVFIVYKSCAYGCRKC 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	GT1_Gtf-like	18..449	CDD:340817	106/469 (23%)
Ugt1a3	NP_958827.1	UDPGT	26..522	CDD:278624	132/527 (25%)