DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35D1 and ugt-35

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001023694.1	Gene:	ugt-35 / 3565443	WormBaseID:	WBGene00044286	Length:	536	Species:	Caenorhabditis elegans

Alignment Length:	554	Identity:	132/554 - (23%)
Similarity:	233/554 - (42%)	Gaps:	67/554 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSP--YPQREPFR---- 62
            :|.|:.:|...|:....|...||.:.||:.|......:|:..||.:|.::|  ..:.|.|:
Worm     8 LFFLISILFQNSKSVNFLVYCPLFAHSHHTFLAKIADTLSEEGHNVTFLAPIIVQKYENFKYLKH 72

  Fly    63 --NIHDIPVPEVFENFNEVLRIASTPRSTWQSSDFINEYV--LNLTKTVLNN--EGVRRD--ILG 119
              :|..|...|..:...|::..|...: .|.....:...:  :.|.:.:.:.  |.:|.|  ||.
Worm    73 TTDIIYIQPDEELKKLGEIMGSAGFSK-YWTEEPSVFSMIPSIKLFQKMFHKIYENLRADLSILD 136

  Fly   120 PQKPH-FDLVIMDLWRMDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNVSPISYLQSPSSRFYD 183
            ..|.. ||.:|.::...:.:: :..|     :|:.:....:.:...|.....|....||::....
Worm   137 SLKDRKFDAMIYEVLAFNAIA-IQQY-----LGIKTLYPTFSVTHGMVLSKSIGEPASPATLSSA 195

  Fly   184 LEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQFFPSVAERKP--------------LSEISR 234
            |..|||:           ||::.|.:........|.|     .||              |.|...
Worm   196 LSPYGEK-----------MNFQERLMNTVCAFIYQVF-----MKPPKMISYSHPYYEIDLKEAES 244

  Fly   235 NFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHS---TEALSAELDHFIQGAGESGVIYFSLGTN 296
            ....|.:|.:..|..|||.:...:.:||:.|:.|   .|.||.|..:.:....::  :..|.|:.
Worm   245 KASFVFLNSNPYLDFPRPMLTKTVLIGGISVNTSQIREERLSDEYHNILNIRVKT--VLISFGSI 307

  Fly   297 VKSKSLSEDRRKVLLETFASLPQ-RIVWKFE-DEL-LPGKPPNVFISKWFPQQAILAHPNVKLFI 358
            :.|..:.:..:.::::.....|. ..:||:| ||| ......|:...||.||.|:||...:..||
Worm   308 MLSTDMPDRYKSIIVKVIEEFPNVTFIWKYESDELDFANNLKNLHFFKWIPQTALLADSRLSAFI 372

  Fly   359 THGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTS-EEFRSTIIRLLTNK 422
            ||.||.|..|..:.|||.:.:|...||.||...:.:....:.|..:.:.: |:.|.::.::|.:.
Worm   373 THAGLGSINELSYMGKPAILVPIFADQLRNAKMLVRHNGSISLEKQDLGNFEKLRVSLAKILKDN 437

  Fly   423 SFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFLVGA 487
            ||:|.|.|.|.:..:||:.|.|..|....:.........:....:.:.|...:.:|:|  ..:|
Worm   438 SFQENAEILARQLNNQPISPRELLIKHATFGAEFGELPSLDPYSRQMSFFSLNMIDIF--LFLG- 499

  Fly   488 LVILGIVTYLLVMTLRKCLFLIKRGKCEAIKKIQ 521
             |.|.|:.|.|...||..|.|:.:.|  |::|.|
Worm   500 -VFLAILVYFLFTFLRLLLNLLLKKK--AVEKSQ 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	115/493 (23%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	121/516 (23%)
ugt-35	NP_001023694.1	Glycosyltransferase_GTB_type	2..464	CDD:299143	115/480 (24%)
ugt-35	NP_001023694.1	UDPGT	34..506	CDD:278624	115/500 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810