Protein Alignment Ugt35D1 and Ugt2b10

DIOPT Version :10

• Sequence 1: NP_651866.1
• Gene: Ugt35D1 / 43708
• FlyBaseID: FBgn0051002
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001178605.1
• Gene: Ugt2b10 / 305264
• RGDID: 1309989
• Length: 532
• Species: Rattus norvegicus
• Alignment Length: 557
• Identity: 168/557 - (30%)
• Similarity: 267/557 - (47%)
• Gaps: 95/557 - (17%)

  Fly     6 LLVCLLP-----GYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSP----------- 54
            ||:.||.     |...|.::| |:|: ..||:......|..|...|||:|.:.|
  Rat     9 LLLLLLQLSDFFGSGTGGKVL-VWPM-EFSHWLNLRVILDELLKKGHEVTVLRPSASLSYEVDNT 71

  Fly    55 -------YPQREPFRNIHDIPVPEVFENFNEVLR--IASTPRST------------WQSSDFINE 98
                   ||.        ...:.||.|.|.|.||  |...|:.:            |..||
  Rat    72 SAIEFETYPT--------SYSLTEVDEFFWESLRKYIYELPKQSFWGYFLMFQELVWVDSD---- 124

  Fly    99 YVLNLTKTVLNNEGVRRDILGPQKPHFDLVIMDLWRMDVLSG--LAAYFDAPIIGMASYGTDWKI 161
            |..:|.|.|:.|:.:...:   |...||:::.|.:   :..|  ||.....|::....:......
  Rat   125 YFESLCKDVVFNKELMTKL---QNSGFDVILADPF---IPCGDLLAEILKIPLVYSLRFFPGSTY 183

  Fly   162 DELMGNV-SPISYLQSPSSRFYDLEAYGERLLHLM-----ERTFSYMNYKWRHVRKQETLYSQFF 220
            ::..|.: .|.||:....|...|...:.||:.|::     :..|...|.|     |...||::.
  Rat   184 EKYSGGLPMPPSYVPIAMSELSDRMTFVERMKHMIYVLCFDFWFQAFNEK-----KWNELYTEV- 242

  Fly   221 PSVAERKPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGE 285
              :.....|||.....|:.|:..::.|..|.|.:||...|||||. ...:.|..|::.|:|.:||
  Rat   243 --LGRPTTLSETMAKADIWLIRTYWDLEFPHPVLPNFDFVGGLHC-RPAKPLPKEIEDFVQSSGE 304

  Fly   286 SGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKPP-----NVFISKWFPQ 345
            .||:.||||:.|  .:|:|:|..|:....|.:||:::|:||     ||.|     |..:.||.||
  Rat   305 HGVVVFSLGSMV--GNLTEERANVIAAGLAQIPQKVLWRFE-----GKKPETLGSNTRLYKWIPQ 362

  Fly   346 QAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEE 410
            ..:|.||..:.||||||.....|:|:||.|::|:|...||:.|:.|::..|..:.|:...|:|.:
  Rat   363 NDLLGHPKTRAFITHGGTNGIYEAIYHGIPVVGIPLFGDQYDNIVHLKTKGAAVRLDFLTMSSTD 427

  Fly   411 FRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYH 475
            ..:.:..:..:.|::|.|...:..:.|||:||::.|::|.|:|:.||||.|::||..||.:|:||
  Rat   428 LFTALKTITNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWVQYH 492

  Fly   476 SLDVFGTFLVGALVILGIVTYLLVMTLRK-CLFLIKR 511
            ||||.| ||:..     :||.:.:  |:| |||..::
  Rat   493 SLDVIG-FLLAC-----VVTVMFI--LKKCCLFCCQK 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	GT1_Gtf-like	18..449	CDD:340817	133/475 (28%)
Ugt2b10	NP_001178605.1	UDPGT	26..529	CDD:278624	162/540 (30%)