Protein Alignment Ugt35D1 and Ugt2a3

DIOPT Version :10

• Sequence 1: NP_651866.1
• Gene: Ugt35D1 / 43708
• FlyBaseID: FBgn0051002
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001129341.1
• Gene: Ugt2a3 / 289533
• RGDID: 1308444
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 555
• Identity: 165/555 - (29%)
• Similarity: 274/555 - (49%)
• Gaps: 70/555 - (12%)

  Fly     4 IFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYP-------QREP- 60
            ||||.....|....:::| |:|. ..||:......|:.||:.|||:| |..||       :..|
  Rat    10 IFLLQLCWSGCGICSKVL-VWPC-DMSHWLNLKTILEELAARGHEVT-VLKYPSIIIDQSKLTPL 71

  Fly    61 -FRNIHDIPVPEVFEN-FNEVLRIAST--PR-STWQSSDFINEYVLNLT-------KTVLNNEGV 113
             |.||..:...||.|| .||::.:|..  |. |.|:::..:.::.|.||       ::.|.|:.:
  Rat    72 QFENIPVLYETEVAENHLNEIVNLAVNVIPNLSLWEAARTLQDFFLQLTGNFEDLCRSTLYNQTL 136

  Fly   114 R---RD------ILGPQKPHFDLVIMDLWRMDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNVS 169
            .   ||      :|.|..|..:||             |.....|.:....:...:.:::..|.:.
  Rat   137 MNKLRDAKYDVMVLDPVIPCGELV-------------AEVLQIPFVNTLRFSMGYSMEKYCGQLP 188

  Fly   170 -PISYLQSPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQFFPSVAER-----KP 228
             |:||:........|...:.||:.::|...|    :::...:.....:.||:.....|     |.
  Rat   189 VPLSYVPVVMGELTDHMTFTERVKNMMLSLF----FEFWLQQYDFAFWDQFYSKTLGRPTTFCKT 249

  Fly   229 LSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGVIYFSL 293
            :.:.    ::.|:..::.:..||||:||...|||||. ...:.|..||:.|:|.:||.||:.|||
  Rat   250 VGKA----EIWLIRTYWDIEFPRPYLPNFEFVGGLHC-KPAKPLPKELEEFVQSSGEHGVVVFSL 309

  Fly   294 GTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKP----PNVFISKWFPQQAILAHPNV 354
            |:.:  |:|:|::..::....|.:||:::|::..:    ||    ||..|..|.||..:|.||..
  Rat   310 GSMI--KNLTEEKANLIASALAQIPQKVLWRYSGK----KPATLGPNTRILNWIPQNDLLGHPKT 368

  Fly   355 KLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLL 419
            :.||||||.....|:|:||.||:|:|...||..|:.|:...|..:.:.|..|||.:..|.:..::
  Rat   369 RAFITHGGTNGIYEAIYHGVPMVGIPMFGDQPYNIAHMEAKGAAVKVAINTMTSADLLSALRAVI 433

  Fly   420 TNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFL 484
            ...|::|.|...:..:.|||:||::.|::|.|:|:.||||.|::||..||.:.:||||||.|..|
  Rat   434 NEPSYKENAMRLSRVHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLL 498

  Fly   485 VGALVILGIVTYLLVMTLRKCLFLIKRGKCEAIKK 519
            |..:.:..::|...:...|||....::.|....||
  Rat   499 VCVVTLTFVITKCSLFMCRKCCLRERKKKGNRKKK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	GT1_Gtf-like	18..449	CDD:340817	132/469 (28%)
Ugt2a3	NP_001129341.1	UDPGT	25..519	CDD:278624	155/524 (30%)