DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35D1 and ugt-59

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_501911.1	Gene:	ugt-59 / 187799	WormBaseID:	WBGene00011238	Length:	506	Species:	Caenorhabditis elegans

Alignment Length:	540	Identity:	118/540 - (21%)
Similarity:	208/540 - (38%)	Gaps:	100/540 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRNIHDIPVP 70
            ||||.:........||...|..|.||..|.....:.||:.||::|.:        ...:.|..:.
Worm     9 LLVCTIINEFYTLNILFYVPTLSHSHISFNTKLAQLLATSGHQVTVL--------LAQVDDALLI 65

  Fly    71 EVFENFNEVLRIASTPRSTWQSSDFINEYVLNLTKTVLNNEGVRRDILGPQKP------------ 123
            |...:|..:.:....||.             :|.:.:.:|.|...| ..|..|
Worm    66 ENATDFAVLRKKVGVPRG-------------HLRQVLWSNPGPYED-SSPLNPRIFYKLLKVSGT 116

  Fly   124 -----------HFDLVIMDLWRMDVLSGLAAYFDAPIIGM-ASYG---TDW--------KIDELM 165
                       |..|..:...:.||  ||...:|:...|: .|.|   |.|        ...|.:
Worm   117 FVTACQNMAFDHLFLSSLQQQKFDV--GLVEQYDSCGFGIFKSIGIENTVWLSATAIYRPQAEAL 179

  Fly   166 GNVSPISYLQSPSSRFYDLEAYGERLLHLM--ERTFSYMNYKWRHVRKQETLYSQFFPS--VAER 226
            |...|.||:....:.|.|..::.:::::::  :.|...::           ::.|.|.|  ....
Worm   180 GVHLPYSYVPELFAHFSDKMSFFQKVINILIGQATSFVLD-----------VFVQGFQSRIFGFE 233

  Fly   227 KPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHF---IQGAGESGV 288
            :.|..||:....||:|.........|.......:||:.||...:    :||.:   |..:.|:|.
Worm   234 QGLGAISQETSSVLINSVPFFDYSMPVSHQFSNIGGITVDKRDK----KLDPYWQSIADSAENGF 294

  Fly   289 IYFSLGTNVKSKSLSEDRRKVLLETFASLPQ-RIVWKFE--DELLPGKPPNVFISKWFPQQAILA 350
            :..|.|...::..::|..:::..::||.... ..:.|:|  .......|.||.::.|.||..::|
Worm   295 VLVSFGGIARTVDMTESMQRIFYDSFARFSHITFIVKYETSSNSTISVPDNVILTPWIPQLPLMA 359

  Fly   351 HPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTI 415
            |.|.|..|||||..|.:|:..|.|||:.:|...|..:|.......|:.::|:..:::.......|
Worm   360 HKNYKTIITHGGWSSILETTMHSKPMILMPLFADHAKNSKVAESKGVAVLLDKMRLSRRRVVHAI 424

  Fly   416 IRLLTNKSFEETARITAARYRDQPMKPMETAIWW---TEYVLSHKG-AAHMQVAGKDLGFVRYHS 476
            ..:|||..:.:.....:..:.|.|: |.|..|.|   .....|.|. |.|::....|..:::
Worm   425 YTILTNPKYTQNCEKFSRMFSDTPI-PHEELIEWRIRQAAKPSRKAFAKHLRPKEPDFSYLK--- 485

  Fly   477 LDVFGTFLVGALVILGIVTY 496
                    :|.|:|..::.|
Worm   486 --------LGFLIIPAMILY 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	112/504 (22%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	110/516 (21%)
ugt-59	NP_501911.1	UDPGT	33..490	CDD:278624	107/507 (21%)
ugt-59	NP_501911.1	Glycosyltransferase_GTB_type	<247..492	CDD:299143	62/260 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910