DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35D1 and ugt-19

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_500912.2	Gene:	ugt-19 / 187129	WormBaseID:	WBGene00019515	Length:	532	Species:	Caenorhabditis elegans

Alignment Length:	559	Identity:	127/559 - (22%)
Similarity:	214/559 - (38%)	Gaps:	114/559 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRNIHDIPVPEV 72
            :|....|    :||....|...||..|.......|...||.:|.|.|         :.|..:...
Worm    14 ICFASSY----KILFYTNLFGHSHVKFLGAAADILTDAGHNVTVVMP---------VFDDSIKTS 65

  Fly    73 FENFNEVLRIASTPRSTWQSSDFINEYVLNLTK--------------TVLNNEGVRRDILGPQ-- 121
            .::...::.:        .|||.:..:....||              |:|...|:..:....|
Worm    66 LKSTKNIIFV--------NSSDDVAAFAKARTKMLNNLWTMDNTNPFTMLTRVGMMSNTFSSQCK 122

  Fly   122 -------------KPHFDLVIMDLWRMDVLSGLAAY--FDA----PIIGMASYGTDWKIDELMGN 167
                         ..::||.:.:.:      .|.||  |:|    ..:|:.|......:.:::|.
Worm   123 KVLTNTELIETMKAENYDLAVTEPF------DLCAYPFFEAINIRAHVGILSSSRLDHVSDVIGQ 181

  Fly   168 VSPISYLQSPSSRFYDLEAYGERLLHLMERT-----FSY-----------MNYKWRHVRKQETLY 216
            .:..||.....|...|.....:|.:::::..     |||           :|.|||..|
Worm   182 PAAPSYNPGLMSTNSDRMTMWQRFVNVIQYACGSYFFSYIGDREAEVVKEINPKWRSWR------ 240

  Fly   217 SQFFPSVAERKPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAE------ 275
                          |:......::.||...|..|.|....:|.:|||.|....::|..|
Worm   241 --------------EVVPEASFIMTNQIPLLDFPAPTFDKIIPIGGLSVKTDKKSLKLEEKWSKI 291

  Fly   276 LDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQ-RIVWKFED--ELLPGKPPNV 337
            ||  |:...    ::.|.|:|.:|..:..:.:...|:...|:|. ..:||:||  :.......||
Worm   292 LD--IRKKN----VFISFGSNARSVDMPLEYKNTFLQVIKSMPDTTFIWKYEDLNDKFTEGIENV 350

  Fly   338 FISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLN 402
            ::..|.||..:||...:.:|:|||||.|..|....|.|.:.:|...||.||...:::.|...||.
Worm   351 YLGDWLPQNELLADKRLNVFVTHGGLGSVTELSMMGTPAVMIPLFADQSRNGQMLKRHGGVAVLK 415

  Fly   403 IKQMTSEEF-RSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAG 466
            ...::..:. :|||..:|.|..:.::|...|...|:||..|.||.:.:.|:.........|...|
Worm   416 KTDLSDAKLVQSTIEEVLNNPEYRKSAERVAEMLRNQPTNPKETFLKYVEFTARFGKLPSMDNYG 480

  Fly   467 KDLGFVRYHSLDVFGTFLVGALVILGIVTYLLVMTLRKC 505
            :.|.||:|..||:.....:..:|.|.|...::..|::||
Worm   481 RQLTFVQYFFLDIISIISLITVVFLYISYKVIRCTIKKC 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	113/514 (22%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	122/537 (23%)
ugt-19	NP_500912.2	egt	1..472	CDD:223071	113/510 (22%)
ugt-19	NP_500912.2	UDPGT	32..521	CDD:278624	122/537 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810