DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35D1 and ugt-32

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_504060.2	Gene:	ugt-32 / 185911	WormBaseID:	WBGene00018543	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	602	Identity:	145/602 - (24%)
Similarity:	234/602 - (38%)	Gaps:	156/602 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPPIFLLVCLLPGYS--EGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRN 63
            |..:|.|:.|...:|  :..|:|...|..::||..|......:|...||.:|..:|
Worm     1 MALLFKLMILYSVFSNTDSLRVLVYSPAYAASHTNFMARLADTLTEAGHNVTFFTP--------- 56

  Fly    64 IHDIPVPEVFENFNEVLRIASTPRSTWQSSDFINEYVLNLTKTVL---NNEGVRRDILGPQKPHF 125
                              |....|.        :::.:.|||.||   .:|.|:|:.:     ..
Worm    57 ------------------IIDESRK--------DQFGVKLTKDVLILEQDEQVKRNPV-----TI 90

  Fly   126 DLVIMDLWRMDVLS--------------------------------------GLAAYFDAPII-- 150
            |..:...|..||.|                                      |||    .|::
Worm    91 DNDMKYFWTTDVTSANGHKVMGTLHKQAIFTCENVFKHQELIDELRSRNYDIGLA----EPLMTC 151

  Fly   151 GMASY---GTDWKIDELM---------------GNVSPISYLQSPSSRFYDLEAYGER-----LL 192
            |:|.:   |    |:::|               |.....||..|.:|:..|:.::.:|     |.
Worm   152 GLALFRHIG----IEKVMLTTSCTNYDILLPATGEPEDTSYNPSMNSQVTDVMSFWQRLENYDLY 212

  Fly   193 HLMERTFSYMNYKWRHVRKQETLYSQFFPSVAERKPLSEISRNF-DLVL-VNQHFT-----LGPP 250
            |:|..||             ||::..  .:...||.|.|...:: ||:. .:.|||     |..|
Worm   213 HVMIPTF-------------ETIFDD--EANVYRKYLGESFPDWRDLIPDASLHFTNSIPFLDFP 262

  Fly   251 RPYVPNMIQVGGLHVD-HSTEALSAELDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETF 314
            ||.:...|::||:.|| .|...::.|..:.:.....:.:|  |.|:..:|..:....::.||..|
Worm   263 RPSIQKTIEIGGIAVDIESIPPVNEEFSNILDKRPMNMLI--SFGSLARSTEMPIIFKENLLRVF 325

  Fly   315 ASLPQ-RIVWKFE--DELLPGKPPNVFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPM 376
            .|.|. ..:||:|  |........||...||.||.|||....:..|:|||||.||.|:...|||.
Worm   326 QSEPNCTFIWKYESDDVAFANDVENVIFVKWMPQTAILKDNRLTAFLTHGGLGSTNEAAFLGKPS 390

  Fly   377 LGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTS-EEFRSTIIRLLTNKSFEETARITAARYRDQPM 440
            :..|...||.||.:.:.:..:.:||:...:.: ::.|.....:|.|:.:...||..|...|:||.
Worm   391 VMFPIFADQSRNSNMLGRQEMSIVLHKSDLGNFQKIRDAFHEILHNEKYHLNARKVADMVRNQPA 455

  Fly   441 KPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVF-GTFLVGALVILGIVTYLLVMTLRK 504
            ||.:..:...|:|.......||......:.|.:.:..|:| ..||....:   .|.:||.:|  |
Worm   456 KPRDIFVKHVEFVGRFGPLHHMTPYSLKMPFYQRYHYDIFIFKFLTNYFI---PVVFLLCVT--K 515

  Fly   505 CLFLIKRGKCEAIKKIQ 521
            .:|    .|.: :|||:
Worm   516 LIF----SKFQ-LKKIK 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	128/540 (24%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	133/559 (24%)
ugt-32	NP_504060.2	Glycosyltransferase_GTB_type	1..508	CDD:299143	135/574 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810