DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35D1 and ugt-40

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_504810.2	Gene:	ugt-40 / 184292	WormBaseID:	WBGene00017331	Length:	526	Species:	Caenorhabditis elegans

Alignment Length:	566	Identity:	132/566 - (23%)
Similarity:	228/566 - (40%)	Gaps:	115/566 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRN----- 63
            ::|...||...:....||...||...||..|.......|...||.:|..||....| |||
Worm     6 LYLYYLLLISSTTSYNILVFCPLFGHSHSTFFGRLADILTEAGHNVTLFSPTIIDE-FRNYSYTK 69

  Fly    64 -IHDI----PVPEVFENFNEVLRIASTPRSTWQSSDF-------INEYVLNLTK---TVLNNEGV 113
             ..|:    |.||: :...::  ||...|  |.:.:|       ...:..::|:   .||.|...
Worm    70 LTKDVAYLDPSPEL-KAIGDL--IAGNKR--WWNQEFSVFEIPQTTRFFKSITREQNNVLANNLA 129

  Fly   114 RRDILGPQKPHFDLVIMD------LWRMDVLS----GLAAYFDAPIIGMASYGTDWKIDELMGNV 168
            ..|  |.::..|||::.:      |..|:.|.    .:|.......|.:.:.|     |.:|  .
Worm   130 LLD--GLKQKKFDLILFESVFTCALPLMEYLEIKSFAVAQSIAYEPITLGALG-----DTVM--T 185

  Fly   169 SPISYLQSPSSRFYDLEAYGERLLHLMERTFSYM-----NYKWRHVRKQETLYSQFFPSVAERKP 228
            |.|..|.:.||   |..:..||:|:.:.:....:     .|...:...::.:|:        .:.
Worm   186 SHIPNLMAQSS---DKMSLCERMLNTLIQAMLNVYGMTPEYYQSYTNPEKKIYT--------LEK 239

  Fly   229 LSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVD----HSTEALSAELDHFIQGAGESGVI 289
            |||.|    .:.:|.:..|..||..:...||:||:.|:    .|:..|:.|.|..:
Worm   240 LSEAS----FIFMNSNPFLDFPRATITKNIQIGGISVNLDTLKSSGKLTEEWDQIL--------- 291

  Fly   290 YFSLGTNVKSKSLSEDRRKVLLETFASLPQRI--------------VWKFE----DELLPGKPPN 336
                  |::.|:|......|:|........::              :||:|    .|...| ..|
Worm   292 ------NLREKTLLVSFGSVILSQDMPFAYKVGLTNAMKQLNDVTFIWKYEGDDKKEFANG-IKN 349

  Fly   337 VFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLV- 400
            :..|||.||:.:||.|.:..|:|||||.|..|..:.|||.:..|...||.||...:.:.. |.:
Worm   350 IHFSKWVPQRELLADPRLSAFMTHGGLGSVNEVSYFGKPTIMCPLSGDQMRNAKMLERHN-GSIE 413

  Fly   401 -----LNIKQMTSEEFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAA 460
                 |:.:::.:..||    ::|.::|:..:|:..:...:.||:||.|..:...|:........
Worm   414 FSKYDLHNEKVVANAFR----KILYDESYTLSAKRLSEHLQFQPVKPKELFLKHVEFAARFGKLP 474

  Fly   461 HMQVAGKDLGFVRYHSLDVFGTFLVGALVILGIVTYLLVMTLRKCL 506
            .:....:.:||::|..:|:....|...|.|:.:: |.::..:..||
Worm   475 SLDPYSRQMGFIQYFLIDIAFIVLTVVLTIVSVL-YFVLKFVASCL 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	122/520 (23%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	125/540 (23%)
ugt-40	NP_504810.2	YjiC	22..447	CDD:224732	113/475 (24%)
ugt-40	NP_504810.2	Glycosyltransferase_GTB_type	<247..503	CDD:299143	66/276 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810