DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35D1 and ugt-65

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_502373.3	Gene:	ugt-65 / 184205	WormBaseID:	WBGene00008583	Length:	509	Species:	Caenorhabditis elegans

Alignment Length:	540	Identity:	132/540 - (24%)
Similarity:	222/540 - (41%)	Gaps:	91/540 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEIT--SVSPYPQREPFRNIHD 66
            ||||...|. .|..:|||.:....|.||....:|..:.|...||:::  ::|....:.|.:.:
Worm    11 IFLLAHFLT-TSNCSRILFLNMFNSKSHALTMMPLAERLFDDGHDVSMYTISANRLKIPSKKV-- 72

  Fly    67 IPVPEVFENFNEVLRIAST----------PRSTW--QSSDFINEYVLNLTKTVLNNEGVRRDILG 119
                ::.|:   :::.:||          .|..|  :.:.::..:...:....| .||....:..
Worm    73 ----KILES---LVKGSSTDDAAPDTGGVSRIFWSYEMTPYVGAWCYEIGLYYL-EEGRDEQLDE 129

  Fly   120 PQKPHFDLVIMDLWRMDVLSGLAAYF----DAPIIGMASYGTDWKIDELMGNVSPI-SYLQSP-- 177
            .....:||.::|.....:...:|...    ...||..|:       .|||...|.: .|.::|
Worm   130 VLATPYDLAVVDETYTSLQGSIALKLKEDHSTKIITFAT-------TELMPVASNMRGYARNPVT 187

  Fly   178 -------SSRFYDLEAYGERLLHL--MERTFSYMNYKWRHVRKQETLYSQFFPSVAERKPL---- 229
                   ||..|:    |.|...|  ..|.|.|. ....:.....:|||:     |..|.|
Worm   188 VPNTFLLSSEVYE----GNRFAFLTRTRRIFEYF-IDQIYSGPVASLYSE-----ASGKLLGLTS 242

  Fly   230 SEISRNF--DLVLVNQH---FTLGPPRPYVPNMIQVGGLHVDH--STEALSAELDHFIQGAGESG 287
            :..|:.|  .::.||..   |:...||.  .::|:||    :|  |:..|.:|...|::.:...|
Worm   243 ATKSKTFQNSILTVNDFPDTFSFVQPRG--NDLIRVG----EHCYSSANLPSEFRDFVEDSMSKG 301

  Fly   288 VIYFSLGTNVKSKSLSEDRRKVLLETFASL-----PQRIVWKFEDELLPGKPPNVFISKWFPQQA 347
            .||.::|:.:.    .||..|..:|.|...     ..|::|..:.. :.|...:|....|.||:.
Worm   302 TIYVAMGSYLN----LEDGPKGTVEAFIEALNYFKDYRVIWSHKGN-VTGAKCHVKSVNWAPQKE 361

  Fly   348 ILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFR 412
            :|||.....|||||||.|..|.:..|.|||.||...||.||.......|:...|..|.:||.:.:
Worm   362 LLAHEKTVAFITHGGLKSAKEGVCSGVPMLFLPFYGDQPRNAHRFVTNGIAEALYKKAITSLDIQ 426

  Fly   413 STIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKD--LGFVRYH 475
            ..:.:||.:.|::.......:.|.|.|:..::...:....||....:.:.:...:.  :..::|.
Worm   427 QKLEKLLVDPSYKNNVMKVLSYYLDAPISSLDLGAFHISQVLRRTESQYSKFKRRSIFMNHLQYL 491

  Fly   476 SLDVFGTFLVGALVILGIVT 495
            :||:   ||| .||||.||:
Worm   492 NLDI---FLV-ILVILFIVS 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	120/503 (24%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	122/514 (24%)
ugt-65	NP_502373.3	egt	<300..505	CDD:223071	61/213 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010