DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35D1 and ugt-17

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001122841.1	Gene:	ugt-17 / 179406	WormBaseID:	WBGene00007422	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	580	Identity:	139/580 - (23%)
Similarity:	236/580 - (40%)	Gaps:	111/580 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRNIHDIP 68
            ||:|..:: .||...::|...|...:||..|.......|...||::|.:.|...:   ...|.:.
Worm     8 IFILFSII-DYSNSYKVLVFNPAFGASHSNFLGKISDILIDAGHDVTMLIPIAMQ---GKKHLVG 68

  Fly    69 VPEVFENFNEVLRIASTPRS----------------TWQ-SSDFINEYVL--NLTKTV------- 107
            ..:|    ..::||...|||                .|: .||....:.:  |.:||.
Worm    69 SKKV----KNIIRIDQDPRSIELYKQTGAEDVLRKKIWKVESDIALFFKMAGNFSKTCGYQCQHV 129

  Fly   108 ---------LNNEGVRRDILGPQKPHFDLVIMD-LWRMDVLSGLAAYFDAPIIGMASYGTDWKID 162
                     |.||            ||:|.|.: |:       :..|   |:.......|....|
Worm   130 FQQTEILEKLKNE------------HFELGITESLF-------ICGY---PLFDHLGVKTIINAD 172

  Fly   163 E-LMGNVSPISYLQSPSSRFY--------DLEAYGERLLHLMERT----FSYMNYKWRHVRKQET 214
            . |..::...:..:..||.||        |.....||:.:.::..    ||.|.:       :|.
Worm   173 SVLFMDIVKCTLGEPSSSTFYPALISPMTDKMTLVERIKNAIQMLIPVYFSKMRF-------EEE 230

  Fly   215 LYSQFFPSVAERKPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHV---DHSTEALSAEL 276
            | |...|.....|...|:..|....:||.:..|....|.:|..:.:||:.|   ...|..|:.|.
Worm   231 L-SMIEPYYNGSKTWEELLENVAFNMVNSNRYLDYASPTLPKTVFIGGMQVKTKKQGTPKLNKEW 294

  Fly   277 DHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQ-RIVWKFEDE--LLPGKPPNVF 338
            |..:....|:  :..|.|:|..|..:.::.:|..|:.|||:|: ..:||:|.|  .:.....||.
Worm   295 DDLLNIRKEN--VLVSFGSNAFSSEMPDEFKKSFLDVFASMPEITFIWKYEQENSTIAMHLSNVK 357

  Fly   339 ISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKP----MLGLPCLFDQFRNMDHVRQVGLGL 399
            ::.|.||..:||...:.||:|||||.|:||..:.|.|    :..:|.:.||.||...:.:.|..:
Worm   358 MTTWMPQSDLLADNRLSLFVTHGGLGSSIELAYQGTPAVVNIFKIPLMADQPRNAHMLTRHGGAI 422

  Fly   400 VLNIKQMTSEE-FRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQ 463
            .|:...:.:.: .|..|..:|.|.|:.|.||..|....|||..|.|..:...::.:.......:|
Worm   423 QLDKTNLDNPQMIRDAIKTILDNDSYTENARKLAQILEDQPYTPAEVVLKHCDFAVKFGVLDTLQ 487

  Fly   464 VAGKDLGFVRYHSLDVFGTFLVGALVILGIVTYLLVMTLRKCLFLIKRGKCEAI--KKIQ 521
            ..|:.|...:::|.|:   .:|...:|:.:|.: :|:.:.:|:.:     |..|  ||::
Worm   488 SEGRKLNVFQFYSYDI---LVVVCFLIITVVVF-IVLYVFQCIKI-----CSTIFSKKVK 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	125/517 (24%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	128/540 (24%)
ugt-17	NP_001122841.1	egt	1..513	CDD:223071	132/547 (24%)
ugt-17	NP_001122841.1	UDPGT	22..538	CDD:278624	134/563 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810