DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35D1 and ugt-9

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_504312.1	Gene:	ugt-9 / 178883	WormBaseID:	WBGene00020587	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	560	Identity:	127/560 - (22%)
Similarity:	230/560 - (41%)	Gaps:	78/560 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPPIFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYP--------- 56
            :|...|.:.|:........||...|:...||..|.......:|..||.:|...|:.
Worm     2 LPNNLLSILLVISLVSCKNILVYNPIFGYSHAKFVSQLANIIADHGHNVTVFQPFHIALKNTDGL 66

  Fly    57 -QREPFRNIHDIPVPEVFENFNEVLRIASTPRSTWQSSDFINEYVLN------------------ 102
             :.:....|:..|     :::.|:|:     :.|....||.:.:::|
Worm    67 IKNKNIEIINYYP-----DHYAELLK-----KKTPTFPDFWDSHLMNNPVLSSFLMPKALGGEFE 121

  Fly   103 -LTKTVLNNEGVRRDILGPQKPHFDLVIMDLWRMDVLSG--LAAYFDAPIIGMASYGTDWKIDEL 164
             .|..:..::.:..|:   :..:||:::.:.:.   ::|  :|...:.|.|.:.|......||..
Worm   122 QTTTQLFQDQKILNDL---KNRNFDVLLAETFE---IAGFYIADLLEIPSIPLMSAVRLPIIDSA 180

  Fly   165 MGNVSPISYLQSPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQFFPSVAERKPL 229
            .|..|.:.|.....|:......:.:||..|      |..:.|....::...:...|...|...|:
Worm   181 FGQPSILGYFPQQYSKVAPEAGFLDRLNDL------YRIFFWNLTTQRLCQFQNDFIQKAIGHPV 239

  Fly   230 ---SEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVD----HSTEALSAELDHFIQGAGESG 287
               .::.:...:.:.|.:..|....|....::.|||:.:|    ....||:.|.::.:  |....
Worm   240 PHWRDLVKESPIYITNSNSYLDFAVPTTATIVHVGGITIDLEKMRHVAALTEEYENIL--AERES 302

  Fly   288 VIYFSLGTNVKSKSLSEDRRKVLLETFASLPQ-RIVWKFEDELLPGK---PPNVFISKWFPQQAI 348
            .::.|.|:.::|..:.::.:..:::.|.|||. ..:||:|.:.:..:   |.||.:.||.||.::
Worm   303 TVFISFGSVIRSYEMPDNFKAGIIKMFKSLPDVTFIWKYEKDDVKFQNRLPKNVHLKKWVPQPSL 367

  Fly   349 LAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIK--QMTSEEF 411
            ||...||||:|||||.||:|..:.|||.|.:|...||..|.|.:.:.| |.|...|  ....|:.
Worm   368 LADKRVKLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPNNADMLARHG-GAVAYDKFDLADGEKL 431

  Fly   412 RSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHS 476
            ..|:..::||..:|..|:........||:.|....:...|:.:..........|....|.:.::.
Worm   432 TKTVRDMVTNSKYEVNAQELLKVLSKQPIDPKLNLMKHLEFAMEFPKHRSQVPAINRTGLIAHYY 496

  Fly   477 LDVFGTF----LVGALVILGIVTYLLVM-TLRKCLFLIKR 511
            |||.|..    :.|..||..|:..|..| :|||    :||
Worm   497 LDVIGVLTLASIFGLFVIFKILNILRKMISLRK----VKR 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	110/504 (22%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	119/529 (22%)
ugt-9	NP_504312.1	egt	20..462	CDD:223071	105/466 (23%)
ugt-9	NP_504312.1	UDPGT	30..532	CDD:278624	119/530 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810