DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35D1 and ugt-64

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_503978.1	Gene:	ugt-64 / 178774	WormBaseID:	WBGene00015577	Length:	501	Species:	Caenorhabditis elegans

Alignment Length:	546	Identity:	116/546 - (21%)
Similarity:	208/546 - (38%)	Gaps:	108/546 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGH----EITSVSP---YPQREPF 61
            |..|..|.|.:.:.|::|........||.....|.:..|....|    |:.:..|   :...|.|
Worm     6 ILYLFLLFPNFCDSAKVLLTVMDQGRSHATSITPLMHRLQKNDHTTALEMATYKPDIDFGMEERF 70

  Fly    62 RNIHDIPVPEVFEN---FNEVLRIASTPRSTWQSSDFINEYVLNLTKTVLNNEGVRRDILGPQKP 123
            .|:..      |||   ..:..:||.....|     |:::.|..:..::..:.     ||..||.
Worm    71 INMSG------FENNFISKDFFKIAFEDEFT-----FVHQAVPFIFGSISCDR-----ILKHQKN 119

  Fly   124 HFDLVIMDLWRM---DVLSGLAAYFDAPIIG---MASYGTDWKIDELMGNVSPIS---------Y 173
            .:..:..:.|.:   |.|.....|..|.|.|   :..:.:|  ::...|:....|         :
Worm   120 RYLEIANENWDLFLSDSLFSPCGYAMAEITGKPHVMMHSSD--VESAHGSFKGFSRNYAIMVPNF 182

  Fly   174 LQSPSSRFYDLEAYGERLLHLME--------------------RT------FSYMNYKWRHVRKQ 212
            |....|.| .:|.|..|::..::                    |:      ||:.:|..|
Worm   183 LPYSMSNF-TIEKYWHRVVSTVDWFGSAFITGAVAGFAQKWALRSIIPFPFFSFYDYNRR----- 241

  Fly   213 ETLYSQF-FPSVAERKPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAEL 276
                |.| |..:.:  ||..:...     .|.:|:.              |.:.....:.|..:.
Worm   242 ----SSFSFTDMPD--PLYPVGAR-----TNDYFSF--------------GTYCTAQKKVLDEDW 281

  Fly   277 DHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQ-RIVWKFEDELLPGKPPNVFIS 340
            :.|:......|.|..:.||.:..:...|::.::.|.|...|.: |::|..:.:...|...:|.||
Worm   282 EQFVSDPKSKGTILVAFGTIIDWRFAPEEKFEIFLNTLNRLTEYRVIWSMKGDRPKGLGEHVKIS 346

  Fly   341 KWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQ 405
            .|.|||.||.|....||::||||.|..|::....|.|.:|...:|.||....:..|...:||...
Worm   347 SWVPQQQILNHKKTVLFLSHGGLKSVKEAVCSATPSLFMPMFAEQMRNAWLAKSKGFARILNKFH 411

  Fly   406 MTSEEFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGK--D 468
            ::.:...:.|..::.:||::..|....:.:.||||..::.|.:..|.:..:.|........|  |
Worm   412 LSEQYLENHIREVVEHKSYQIQAEQFLSTFTDQPMPALDEAAFKFERLFKYNGKMPKFFYPKTID 476

  Fly   469 LGFVRYHSLDVFGTFLVGALVILGIV 494
            |.::...:||::    |...::||.:
Worm   477 LSYLTALNLDIW----VIVPLVLGYI 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	108/510 (21%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	110/520 (21%)
ugt-64	NP_503978.1	Glycosyltransferase_GTB_type	<271..468	CDD:299143	51/196 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010