Protein Alignment Ugt35D1 and UGT3A1

DIOPT Version :9

• Sequence 1: NP_651866.1
• Gene: Ugt35D1 / 43708
• FlyBaseID: FBgn0051002
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_689617.3
• Gene: UGT3A1 / 133688
• HGNCID: 26625
• Length: 523
• Species: Homo sapiens
• Alignment Length: 531
• Identity: 140/531 - (26%)
• Similarity: 242/531 - (45%)
• Gaps: 67/531 - (12%)

  Fly     4 IFLLVCLLPG--YSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRNIHD 66
            :.|:..||.|  .||.|:||.:..| ..|||.......:.|...||.:|.:.   |...|.
Human     7 LLLVAFLLSGVLLSEAAKILTISTL-GGSHYLLLDRVSQILQEHGHNVTMLH---QSGKFL---- 63

  Fly    67 IPVPEVFENFN--EVLRIASTPRSTWQSSDFINEYVLNLTKTVLN----NEGV------------ 113
              :|::.|...  :|:|..|......:.....:.|:    :|.|:    :|.:
Human    64 --IPDIKEEEKSYQVIRWFSPEDHQKRIKKHFDSYI----ETALDGRKESEALVKLMEIFGTQCS 122

  Fly   114 ----RRDILGPQK-PHFDLVIMDLWRMDVLSGL-AAYFDAPIIGM--ASYGTDWKIDELMGNVSP 170
                |:||:...| .::|||.::.:  |..|.| |.....|.:.:  .::|:   :|  .|..||
Human   123 YLLSRKDIMDSLKNENYDLVFVEAF--DFCSFLIAEKLVKPFVAILPTTFGS---LD--FGLPSP 180

  Fly   171 ISYLQ-SPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQFFPSVAERKPLSEISR 234
            :||:. .||.....::.:|.....||  .||:...:|......:....:.||. ..|..||.:..
Human   181 LSYVPVFPSLLTDHMDFWGRVKNFLM--FFSFSRSQWDMQSTFDNTIKEHFPE-GSRPVLSHLLL 242

  Fly   235 NFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGVIYFSLGTNVKS 299
            ..:|..||..|.....||.:||.:.:||| ::...:.:..:||:||...|::|.:..:.|:.:.:
Human   243 KAELWFVNSDFAFDFARPLLPNTVYIGGL-MEKPIKPVPQDLDNFIANFGDAGFVLVAFGSMLNT 306

  Fly   300 KSLSEDRRKVLLETFASLPQRIVWKFEDELLPGK---PPNVFISKWFPQQAILAHPNVKLFITHG 361
            .. |::..|.:...||.|||.::|..:....|..   ..||.|..|.||..:||||:::||:|||
Human   307 HQ-SQEVLKKMHNAFAHLPQGVIWTCQSSHWPRDVHLATNVKIVDWLPQSDLLAHPSIRLFVTHG 370

  Fly   362 GLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEE 426
            |..|.:|:|.||.||:|||...||..||..|.....|:.:.:.|:|::....|:.:::.:|.::.
Human   371 GQNSVMEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRLNQVTADTLTLTMKQVIEDKRYKS 435

  Fly   427 TARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFLVGALV-- 489
            .....:.....||:.|.:..:.|.:::|...||.|::.......:...:.:||| .||:|..:
Human   436 AVVAASVILHSQPLSPAQRLVGWIDHILQTGGATHLKPYAFQQPWHEQYLIDVF-VFLLGLTLGT 499

  Fly   490 ------ILGIV 494
                  :||:|
Human   500 MWLCGKLLGVV 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	130/489 (27%)
		UDPGT	30..511	CDD:278624	130/503 (26%)
UGT3A1	NP_689617.3	UDPGT	23..523	CDD:330975	134/515 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150063
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.740