Protein Alignment Ugt35D1 and Ugt1a6

DIOPT Version :10

• Sequence 1: NP_651866.1
• Gene: Ugt35D1 / 43708
• FlyBaseID: FBgn0051002
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_476446.2
• Gene: Ugt1a6 / 113992
• RGDID: 620949
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 542
• Identity: 147/542 - (27%)
• Similarity: 244/542 - (45%)
• Gaps: 71/542 - (13%)

  Fly     7 LVCLLP--------------GYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSP--- 54
            :.||||              |...|.::|.| | ...||:......::.|:..||:|..:.|
  Rat     1 MACLLPAARLPAGFLFLVLWGSVLGDKLLVV-P-QDGSHWLSMKEIVEHLSERGHDIVVLVPEVN 63

  Fly    55 -------YPQREPFRNIHDIPVPEVFENFNEVLR-------IASTPRSTWQSSDFINEYVLNL-- 103
                   |.:|:.|      |||...|......|       .||:|...     .:.||..|:
  Rat    64 LLLGESKYYRRKSF------PVPYNLEELRTRYRSFGNNHFAASSPLMA-----PLREYRNNMIV 117

  Fly   104 -------TKTVLNNEGVRRDILGPQKPHFDLVIMD-LWRMDVLSGLAAYFDAPIIGMASYGTDWK 160
                   .:::|.:......:   ::..||.:..| .....|:  ||.|...|.:.:.. |....
  Rat   118 IDMCFFSCQSLLKDSATLSFL---RENQFDALFTDPAMPCGVI--LAEYLKLPSVYLFR-GFPCS 176

  Fly   161 IDELMG-NVSPISYLQSPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHV-RKQETLYSQFFPSV 223
            ::.::| :.||:||:....::|.|...:.:||.:.:.....  ||.:..: .|.|.|.|......
  Rat   177 LEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIANILE--NYLYHCLYSKYEILASDLLKRD 239

  Fly   224 AERKPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGV 288
            .....|.:.|    |.|:...|....|||.:||||.:||.:...... ||.|.:.::..:||.|:
  Rat   240 VSLPALHQNS----LWLLRYDFVFEYPRPVMPNMIFIGGTNCKKKGN-LSQEFEAYVNASGEHGI 299

  Fly   289 IYFSLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKPPNVFISKWFPQQAILAHPN 353
            :.||||:.|  ..:.|.:...:.|....:||.::|::..........|..:.||.||..:|.||.
  Rat   300 VVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPK 362

  Fly   354 VKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRL 418
            .:.||||.|.....|.|.:|.||:.:|...||..|...:...|.|:.||:.:||:::..:.:..:
  Rat   363 ARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTV 427

  Fly   419 LTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTF 483
            :.|||::|.....::.::|:|::|::.|::|.|||:.||||.|::.|..||.:.:||||||.|..
  Rat   428 INNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFL 492

  Fly   484 LVGALVILGIVTYLLVMTLRKC 505
            |...|.::.||........|||
  Rat   493 LAIVLTVVFIVYKSCAYGCRKC 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	GT1_Gtf-like	18..449	CDD:340817	115/459 (25%)
Ugt1a6	NP_476446.2	UDPGT	26..521	CDD:278624	141/517 (27%)