Protein Alignment Ugt35D1 and ugt1a1

DIOPT Version :10

• Sequence 1: NP_651866.1
• Gene: Ugt35D1 / 43708
• FlyBaseID: FBgn0051002
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: XP_004917944.1
• Gene: ugt1a1 / 100489505
• XenbaseID: XB-GENE-998849
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 538
• Identity: 137/538 - (25%)
• Similarity: 251/538 - (46%)
• Gaps: 89/538 - (16%)

  Fly    16 EGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRNIH----------DIPVP 70
            |..::||: || ..||:......::||...|:::..::|:      .|||          ..|||
 Frog    27 EAEKLLAI-PL-DGSHWLSMRILVESLGQRGNQVVVLAPH------SNIHIHPSENYILRTYPVP 83

  Fly    71 --------EVFENFNEVLRIASTPRSTWQSSDFINEYVLNLTKTV-------LNNEGVRRDILGP 120
                    ::.::.|:|.    |.|........:.:.:.|:|..|       |:::.:.:::
 Frog    84 YSKELLKEQMVKSANDVF----TKRPLLDKITNMYQRITNVTGIVFSACQHLLHSKEIMQEL--- 141

  Fly   121 QKPHFDLVIMD-LWRMDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNV-SPISYLQSPSSRFYD 183
            |:..||..::| .:...::  :|.|...|.:.:. ||....||.|.... ||:||:....:...|
 Frog   142 QESAFDAALIDPFFPCGMI--VAEYLHLPSVYLL-YGLPCGIDRLATQCPSPLSYVPRHFTGNTD 203

  Fly   184 LEAYGER------------LLHLMERTFSYMNYKWRHVRKQET---LYSQFFPSVAERKPLSEIS 233
            ..::.:|            |.:|:...::.:..::.|  ::.|   ||||
 Frog   204 HMSFPQRLKNALLWPVDTFLCNLLYSPYAQLASEFLH--REMTILQLYSQ--------------- 251

  Fly   234 RNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGVIYFSLGTNVK 298
              ..:.|:...|....|||.:|||:.|||::. ...:.|:.|.:..:..:||.|.:.||||:.|
 Frog   252 --TSVWLMKTDFVFDYPRPLMPNMVFVGGINC-VGEQHLNQEFEKLVNSSGEHGFVVFSLGSMV- 312

  Fly   299 SKSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKPPNVFISKWFPQQAILAHPNVKLFITHGGL 363
             ..:..::...:.|...|:||::.|::..:..|....|..:.||.||..:||||..:.||||.|.
 Frog   313 -SEIPMNKAMDIAEALKSIPQKVFWRYTGKAPPNLGENTHLVKWLPQNDLLAHPKARAFITHAGS 376

  Fly   364 LSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEETA 428
            ....|.|.:..||:.:|...||..|...:...|.||.||:..||.|:..:.:..::.|..::|..
 Frog   377 HGIYEGICNAVPMVMMPLFGDQMDNAKRIESRGAGLTLNVLHMTPEDLSNAVRAVINNPVYKENI 441

  Fly   429 RITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFLVGALVILGI 493
            :..::.:.|:|:.|::.|:.|.|:|:.||||.|::.|..||.:.:|:||||.|       .:|.:
 Frog   442 QRMSSLHLDRPIHPLDLAVHWVEFVMRHKGAPHLRPAAHDLNWFQYYSLDVIG-------FLLAV 499

  Fly   494 VTYLLVMTLRKCLFLIKR 511
            :...|.::|:.|.|:.:|
 Frog   500 LLTALFISLKCCTFVFRR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	GT1_Gtf-like	18..449	CDD:340817	113/472 (24%)
ugt1a1	XP_004917944.1	UDPGT	30..525	CDD:278624	136/535 (25%)