DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35D1 and ugt5f1

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	XP_017207383.1	Gene:	ugt5f1 / 100415800	ZFINID:	ZDB-GENE-100406-6	Length:	556	Species:	Danio rerio

Alignment Length:	557	Identity:	154/557 - (27%)
Similarity:	265/557 - (47%)	Gaps:	87/557 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSV----SPY-PQREPFRN 63
            |.:|...||.:.  .:|| ||| ...||:......::.|...||:|:.:    |.| |:..|..:
Zfish    40 IVVLSLTLPVHC--GKIL-VFP-HEGSHWLNLNTLIEELHHRGHQISVIRALDSWYIPETSPHYD 100

  Fly    64 IHDIPV-----PEVFENF-NEVLRIASTPRSTWQSSDF------------INEYVLNLTKTVLNN 110
            ..::|.     .:.:.:| ...|:|....|.|....|.            |.|.|:::   |...
Zfish   101 SINVPFLLGGDDQFYHSFIFRQLQIRREQRWTRFKLDMELKEKFSEMHRKICEMVIHI---VEKE 162

  Fly   111 EGVRRDILGPQKPHFDLVIMDLWRMDVLSG----LAAYFDAPIIGMASYGTDWKIDELMGNV--- 168
            ..:.:.|   ::.:||:::     .|..:|    ||.|...|::    :...|.:.   |..
Zfish   163 PAIMKQI---KEANFDIML-----TDPANGGGVVLAHYLHLPLV----FNVQWTVH---GEAHFA 212

  Fly   169 ---SPISYLQSPSSRFYDLEAYGERLLHLM---ERTFSYMNYKWRHVRKQETLYSQ-----FFPS 222
               ||.||:..|.|:..|..::.:|:.:::   .|.|.|......|       ||.     |.|.
Zfish   213 IAPSPPSYVPFPLSQLTDSMSFPQRIYNVLFSAVRLFLYRRTVGPH-------YSALCNRLFGPG 270

  Fly   223 VAERKPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESG 287
            :    ...|:.:..|:.|:...|....|||.:||:|.:||.|.. ..:||..:|:.|:|.:||.|
Zfish   271 L----DYFELFQAADIWLMRADFVFDFPRPTMPNVIYIGGFHCS-PAKALPKDLEDFLQSSGEHG 330

  Fly   288 VIYFSLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKPPNV----FISKWFPQQAI 348
            ||..||||.|  ..|..|....::..||.|||:::|::..:    :|.||    .:..|.||..:
Zfish   331 VIVMSLGTLV--AQLPMDIADEIVAAFAELPQKVIWRYTGD----RPANVGNNTLLVNWLPQNDL 389

  Fly   349 LAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRS 413
            |.||..::|::|||.....|:|:||.|::|||.:|||..|:..::..|:..||:|..:....|:.
Zfish   390 LGHPKTRVFVSHGGTNGVFEAIYHGVPIVGLPLVFDQDYNLLKMKHKGVAKVLDIATINRNIFKD 454

  Fly   414 TIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLD 478
            .:..:|.:.|:....:..::.::|.|:||:::|::|||:|:.|:||||::.....:.:..|||:|
Zfish   455 ALQEVLNDPSYRSNMQKLSSLHKDTPLKPLDSALFWTEFVMRHRGAAHLRTDSYKMPWYSYHSVD 519

  Fly   479 VFGTFLVGALVILGIVTYLLVMTLRKCLFLIKRGKCE 515
            | |.|||..|..:..:.:.:|..| .|.|..|..:.:
Zfish   520 V-GVFLVSVLCFIVFLMFKIVRCL-CCRFCAKTNRAK 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	138/502 (27%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	144/525 (27%)
ugt5f1	XP_017207383.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584487
Domainoid	1	1.000	252	1.000	Domainoid score	I2043
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.790