DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35D1 and ugt1a6

DIOPT Version :9

Sequence 1:	NP_651866.1	Gene:	Ugt35D1 / 43708	FlyBaseID:	FBgn0051002	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001107366.1	Gene:	ugt1a6 / 100135191	XenbaseID:	XB-GENE-5793241	Length:	531	Species:	Xenopus tropicalis

Alignment Length:	533	Identity:	143/533 - (26%)
Similarity:	250/533 - (46%)	Gaps:	64/533 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRNIHDIPV 69
            |:|:.|  |.::|.|:|.| | ...||:......:..||..||.|....| .....|:::.:..|
Frog    17 FILLAL--GCADGGRLLVV-P-QDGSHWLSMRVLVDRLAQRGHYIVVAIP-EVNMLFKDLDNYKV 76

  Fly    70 --------PEVFEN----FNE---VLRIASTPRSTW-QSSDFINEYVLNLTKTVLNNEGVRRDIL 118
                    .:|.||    .|:   |.||.:...:.| :|.....::|::..:..|.|..:.|::
Frog    77 KTFSSPYSKDVLENRMRRMNQEIFVDRILTEKITFWYESMSNATQWVVSACQHFLQNSTLIREL- 140

  Fly   119 GPQKPHFDLVIMDLWRMDVL---SGLAAYFDAPIIGMASYGTDWKIDELMGNV-SPISYLQSPSS 179
              :|.|||.::.|    .|.   ..:|.:...|.:.... ||.:.:|::.... ||.||:....:
Frog   141 --EKEHFDAMLTD----SVFPCGEIVAEHLSIPSVSFMR-GTIFGMDQIASQTPSPPSYVPRMFT 198

  Fly   180 RFYDLEAYGER----LLHLMERT------FSYMNYKWRHVRKQETLYSQFFPSVAERKPLSEISR 234
            .:.|..::.:|    |:|.:|..      :.|.......::|:.|..|.|             ||
Frog   199 VYTDNMSFSQRVKNFLIHSLEHIVCHIFYYPYAQMASDFLKKEVTAMSLF-------------SR 250

  Fly   235 NFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGVIYFSLGTNVKS 299
            . .:.|:...|....|||.:||:|.:||::. ...:||..|.:..::.:||.|.:.||.|:.|..
Frog   251 T-SIWLMRYDFVFEFPRPIMPNVILIGGINC-AKQKALPQEFEKLVKSSGEHGFVVFSFGSMVSE 313

  Fly   300 --KSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKPPNVFISKWFPQQAILAHPNVKLFITHGG 362
              .:::.|    :.|....:||::.|::..:..|....|..:.||.||..:||||..:.||||.|
Frog   314 IPMNIAMD----IAEALRYIPQKVFWRYTGKAPPNLGDNTHLVKWLPQNDLLAHPKARAFITHAG 374

  Fly   363 LLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEET 427
            .....|.|.:..||:.||.:.||..|...:...|.||:||::.:..::..:.::.::.|.|::|.
Frog   375 SHGVYEGICNAVPMVMLPLIGDQMDNAKRIESRGAGLILNVQNLIPDDLSNAVMAVIDNPSYKEN 439

  Fly   428 ARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFLVGALVILG 492
            .:..::.:||:|::|::.|:.|.|:|:.||||.|::.|..||.:::|.||||....|...|..|.
Frog   440 IQRLSSLHRDRPVQPLDLAVHWVEFVMKHKGAPHLRPAAHDLNWIQYQSLDVMAFLLAVLLTTLF 504

  Fly   493 IVTYLLVMTLRKC 505
            |.........|.|
Frog   505 ISLKCSTFACRCC 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35D1	NP_651866.1	egt	1..462	CDD:223071	128/488 (26%)
Ugt35D1	NP_651866.1	UDPGT	30..511	CDD:278624	134/508 (26%)
ugt1a6	NP_001107366.1	UDPGT	28..527	CDD:278624	138/520 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm9349
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910